{"id":"W1988877261","doi":"10.1016/s0165-4608(03)00217-6","title":"Molecular cytogenetic abnormalities in patients with concurrent chronic lymphocytic leukemia and multiple myeloma shown by interphase fluorescence in situ hybridization: evidence of distinct clonal origin","year":2003,"lang":"en","type":"article","venue":"Cancer Genetics and Cytogenetics","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Ontario Medical Association","keywords":"Biology; Fluorescence in situ hybridization; Chronic lymphocytic leukemia; Chromosomal translocation; Multiple myeloma; Trisomy; Somatic evolution in cancer; Interphase; Cytogenetics; Cancer research; Molecular cytogenetics; Comparative genomic hybridization; Leukemia; Molecular biology; Immunology; Genetics; Chromosome; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002034903,0.0003469307,0.000509729,0.0001765248,0.00004699267,0.00003889596,0.0001648078,0.0001250231,0.00002958151],"category_scores_gemma":[0.0001397029,0.0003187323,0.0000408015,0.0004176185,0.0005676727,0.00005434654,0.000122218,0.0001902936,9.635384e-7],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.01047378,"about_ca_system_score_gemma":0.009009898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003788427,"about_ca_topic_score_gemma":0.0005615114,"domain_scores_codex":[0.9975168,0.0001195159,0.0006076209,0.0005991468,0.0005967315,0.0005602477],"domain_scores_gemma":[0.9987909,0.0001482492,0.0001548271,0.0003917237,0.0002378655,0.0002764699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006993318,0.0001325705,0.9556119,0.001306615,0.00008346545,0.0001103047,0.0004642961,0.006344955,0.0233507,0.00007616977,0.00005480551,0.01176491],"study_design_scores_gemma":[0.06163129,0.003928164,0.3064694,0.004580905,0.0003229233,0.0001612016,0.0002239752,0.06863518,0.5511727,0.00004899523,0.001548168,0.001277087],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9580833,0.04055497,0.0003799774,0.00001847517,0.00007384313,0.0007858895,0.00005686128,0.000009942927,0.00003673792],"genre_scores_gemma":[0.9907241,0.008596075,0.0004139906,0.00005802917,0.00003104892,0.00006243782,0.00003442413,0.00004738194,0.00003248339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6491424,"threshold_uncertainty_score":0.9999264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01824695187360097,"score_gpt":0.2888925608732239,"score_spread":0.2706456089996229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}