{"id":"W1988884001","doi":"10.1093/annonc/mdt358","title":"Equipoise abandoned? Randomization and clinical trials","year":2013,"lang":"en","type":"letter","venue":"Annals of Oncology","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Randomized controlled trial; Medicine; Randomization; Clinical equipoise; Clinical trial; Psychotherapist; Family medicine; Psychology; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.2382636,0.001275001,0.005146846,0.002341127,0.009287219,0.01304901,0.008444325,0.1852346,0.01236041],"category_scores_gemma":[0.515673,0.00289165,0.004613799,0.003217307,0.02983155,0.01687944,0.00816448,0.1109084,0.004997908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01503859,"about_ca_system_score_gemma":0.03383679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007107417,"about_ca_topic_score_gemma":0.0164387,"domain_scores_codex":[0.7191516,0.217073,0.01890162,0.01185403,0.02494915,0.00807061],"domain_scores_gemma":[0.3863755,0.5492484,0.0161955,0.01472193,0.01434407,0.01911457],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007778876,0.000148694,0.002131487,0.0005268122,0.0003734788,0.001698622,0.0008687925,0.0002752631,0.000176392,0.11929,0.8407825,0.03295016],"study_design_scores_gemma":[0.003058946,0.0003310037,0.00179618,0.003196751,0.0004551887,0.002235092,0.0009114968,0.002166608,0.0004094658,0.3422785,0.6428567,0.0003040076],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002996679,0.001749492,0.0004354457,0.9899809,0.005122262,0.00003277256,0.00002408869,0.00001109055,0.002344287],"genre_scores_gemma":[0.004530508,0.0006469539,0.0008081231,0.9760869,0.0161363,0.0001756571,0.00001212308,0.00002012637,0.001583212],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.7617365,"threshold_uncertainty_score":0.9393566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8798660536227575,"score_gpt":0.7276655212249659,"score_spread":0.1522005323977916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}