{"id":"W1988906073","doi":"10.1038/nm.3499","title":"Rejuvenating aged muscle stem cells","year":2014,"lang":"en","type":"letter","venue":"Nature Medicine","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Stem cell; Cell biology; Phenotype; Biology; Protein kinase A; Function (biology); p38 mitogen-activated protein kinases; Myocyte; Kinase; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.000289723,0.000354661,0.000433532,0.00008054212,0.00009864455,0.000005944378,0.0004081923,0.003040577,0.000112222],"category_scores_gemma":[0.0001037782,0.0002775333,0.0001304813,0.00008909026,0.0002048469,0.000001316687,0.00009124747,0.002835459,0.00002661714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001241931,"about_ca_system_score_gemma":0.00004940448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001659409,"about_ca_topic_score_gemma":0.0000113188,"domain_scores_codex":[0.9982471,0.0001908535,0.0002783069,0.0006351844,0.0002660724,0.0003824208],"domain_scores_gemma":[0.998889,0.00007275891,0.0002180705,0.0006699117,0.00008854866,0.00006168724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002242026,0.000007240755,0.00001026619,0.0001140697,0.00004973409,0.0000282359,0.00002225296,0.000002471838,0.1307676,0.000005939789,0.8674858,0.001483983],"study_design_scores_gemma":[0.0007134453,0.0003184703,0.00009980817,0.0001161336,0.00005485843,0.000008482531,0.00002374924,0.00000537751,0.01227172,0.00009620186,0.9859986,0.0002931545],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.04502314,0.0141221,0.0004395929,0.9123178,0.005023588,0.0006966817,0.00004845847,0.0001064739,0.02222219],"genre_scores_gemma":[0.112944,0.0001988457,0.00007171187,0.867985,0.01199237,0.00002100789,0.001373301,0.00006871267,0.005345108],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1185128,"threshold_uncertainty_score":0.9999677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008216028967070467,"score_gpt":0.2470881891978353,"score_spread":0.2388721602307649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}