{"id":"W1988906073","doi":"10.1038/nm.3499","title":"Rejuvenating aged muscle stem cells","year":2014,"lang":"en","type":"letter","venue":"Nature Medicine","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Stem cell; Cell biology; Phenotype; Biology; Protein kinase A; Function (biology); p38 mitogen-activated protein kinases; Myocyte; Kinase; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001618052,0.0005147569,0.0007635913,0.0003099166,0.001152152,0.001574003,0.0009106628,0.01396256,0.003152277],"category_scores_gemma":[0.00619629,0.0002858985,0.0007240018,0.0001753766,0.001675595,0.001160556,0.001064703,0.01133865,0.001817158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001137221,"about_ca_system_score_gemma":0.0007546947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009471898,"about_ca_topic_score_gemma":0.001928354,"domain_scores_codex":[0.9993413,0.000166867,0.0000611083,0.00008079955,0.0002516239,0.00009823027],"domain_scores_gemma":[0.9987724,0.0007075841,0.00008090773,0.0000819687,0.0001836386,0.0001734151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000521697,0.0001623974,0.0009468711,0.000167397,0.00006622116,0.005301158,0.0001375504,0.0002768844,0.004792541,0.01072834,0.902095,0.07480393],"study_design_scores_gemma":[0.0005167906,0.0003533371,0.001218217,0.0001607359,0.00007149296,0.004731403,0.0002160919,0.0007676592,0.004980586,0.0203654,0.9665677,0.00005063068],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.005232643,0.01687649,0.001154322,0.9016774,0.06577872,0.00004631373,0.00008445872,0.00009500659,0.009054581],"genre_scores_gemma":[0.03923175,0.01308522,0.001794247,0.8330815,0.07824577,0.0001608915,0.0000862617,0.00004373261,0.03427074],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01396256,"threshold_uncertainty_score":0.01054543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008216028967070467,"score_gpt":0.2470881891978353,"score_spread":0.2388721602307649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}