{"id":"W1988942618","doi":"10.1002/eji.200737408","title":"Donor double‐negative Treg promote allogeneic mixed chimerism and tolerance","year":2007,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Lawson Health Research Institute; London Health Sciences Centre","funders":"London Health Sciences Centre; Heart and Stroke Foundation of Canada","keywords":"Immunology; Biology; CD8; Perforin; Transplantation; Immune tolerance; Adoptive cell transfer; Major histocompatibility complex; Transplantation Chimera; T cell; Immune system; Medicine; Cell biology; Stem cell; Haematopoiesis; Hematopoietic cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001202147,0.0002045793,0.0003599022,0.0002662776,0.0001839016,0.00001978178,0.0002448304,0.0001067251,0.0004729674],"category_scores_gemma":[0.00009255104,0.0001693576,0.0001316201,0.0001233843,0.0002991389,0.0001977606,0.00008086457,0.0007235662,0.0004074366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004356337,"about_ca_system_score_gemma":0.00003344527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001188391,"about_ca_topic_score_gemma":0.000005524884,"domain_scores_codex":[0.9981287,0.0005431746,0.0007472291,0.0001954715,0.00003670139,0.0003487938],"domain_scores_gemma":[0.9988067,0.000110454,0.000651744,0.0001919123,0.0002078234,0.00003139991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003094903,0.0001297073,0.0003139981,0.000005577127,0.0004930563,0.0001143991,0.001145537,0.000002536209,0.9367495,0.0001775967,0.002550528,0.05522273],"study_design_scores_gemma":[0.007578265,0.002216902,0.1087739,0.00008812026,0.00008747636,0.005152474,0.0009996904,9.81756e-7,0.4930511,0.00003810548,0.3817191,0.0002939425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752551,0.008439682,0.001386228,0.0003699918,0.006622713,0.0001217291,0.000001007908,0.00003231778,0.007771205],"genre_scores_gemma":[0.9926066,0.0005463915,0.0004389969,0.0002411772,0.0001379418,7.169744e-7,0.000008053486,0.0000304238,0.005989699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4436983,"threshold_uncertainty_score":0.6906205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01175293510549496,"score_gpt":0.2248758068123466,"score_spread":0.2131228717068516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}