{"id":"W1988994846","doi":"10.1002/iub.1007","title":"Gene expression‐targeted isoflavone therapy","year":2012,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Plant tissue culture and regeneration","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"Genistein; Isoflavones; Substrate reduction therapy; Genetic enhancement; Gene; Bioinformatics; Signal transduction; Gene expression; Biology; Clinical trial; Pharmacology; Medicine; Computational biology; Cancer research; Enzyme replacement therapy; Cell biology; Biochemistry; Genetics; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001595412,0.0004108805,0.0004556628,0.0005295668,0.00008648612,0.0004178177,0.0003290702,0.0005470943,0.001850253],"category_scores_gemma":[0.0001554388,0.00008204887,0.0003350778,0.0003191236,0.0001325697,0.0003419992,0.0002060463,0.000708962,0.0007073079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003280719,"about_ca_system_score_gemma":0.0002307116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003029185,"about_ca_topic_score_gemma":0.0004805349,"domain_scores_codex":[0.9999236,0.00001472843,0.00001015154,0.00001936919,0.00002005837,0.00001210562],"domain_scores_gemma":[0.999966,0.00001164636,0.000009297531,0.000001350619,0.0000082415,0.000003455686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004690357,0.0001447707,0.0004777389,0.01382571,0.0001762285,0.0007970224,0.0001339007,0.0007670209,0.07709173,0.006050421,0.0270862,0.8729804],"study_design_scores_gemma":[0.0001094521,0.0009392882,0.001920206,0.001500225,0.000332233,0.002912186,0.00008014696,0.00038674,0.02943415,0.001893899,0.9604585,0.00003307558],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004359296,0.9881094,0.001905398,0.0007516128,0.0006658935,0.00002721676,0.0001131317,0.00006278145,0.00400533],"genre_scores_gemma":[0.02105963,0.971454,0.001269056,0.0007369707,0.0004889777,0.00004176258,0.0003037845,0.00001266584,0.00463319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001850253,"threshold_uncertainty_score":0.006189704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05472886325500033,"score_gpt":0.3077228557174845,"score_spread":0.2529939924624842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}