{"id":"W1989000254","doi":"10.1200/jco.2002.08.017","title":"Carcinoembryonic Antigen as a Target for Therapeutic Anticancer Vaccines: A Review","year":2002,"lang":"en","type":"review","venue":"Journal of Clinical Oncology","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Carcinoembryonic antigen; Epitope; Medicine; Immunology; Vaccination; Immunogenicity; Major histocompatibility complex; Antigen; Immunotherapy; MHC class I; Cytotoxic T cell; CD8; Antibody; Cancer; Immune system; Virology; Biology; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004341206,0.0007721845,0.001463112,0.003191902,0.0002474909,0.001057368,0.0006020353,0.001255068,0.002309417],"category_scores_gemma":[0.0007954756,0.0002387795,0.0007489378,0.003374734,0.0002968959,0.001332436,0.0004192418,0.0008712872,0.0006011641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005569753,"about_ca_system_score_gemma":0.001631633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009495889,"about_ca_topic_score_gemma":0.001005816,"domain_scores_codex":[0.9997982,0.0000359087,0.00004946316,0.00003646596,0.00006093578,0.0000190989],"domain_scores_gemma":[0.9994913,0.0002610831,0.00009700214,0.000009894565,0.0001099218,0.00003068927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002097801,0.0001138925,0.0007959207,0.1502484,0.0003876417,0.00058901,0.0001546751,0.0006441147,0.003887216,0.002662153,0.03502182,0.8052852],"study_design_scores_gemma":[0.00004744506,0.0004079854,0.003351405,0.05090042,0.001540305,0.004664005,0.0002195187,0.0003117935,0.001318787,0.00197754,0.9352111,0.00004973727],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001727691,0.9991553,0.0000582312,0.0001958029,0.0001350809,0.000004879969,0.0000160505,0.000003096412,0.00025882],"genre_scores_gemma":[0.0009426981,0.9984158,0.0001200001,0.0002068866,0.0001390957,0.000008580371,0.00002785667,8.498263e-7,0.0001382081],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003191902,"threshold_uncertainty_score":0.007725775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4254338655899674,"score_gpt":0.6138707632001857,"score_spread":0.1884368976102183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}