{"id":"W1989025636","doi":"10.1159/000119755","title":"Increased Matrix Metalloproteinase 2 Activity in the Human Internal Mammary Artery Is Associated with Ageing, Hypertension, Diabetes and Kidney Dysfunction","year":2008,"lang":"en","type":"article","venue":"Journal of Vascular Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Medicine; Diabetes mellitus; Internal medicine; Renal function; Endocrinology; Ageing; Kidney disease; Endothelial dysfunction; Matrix metalloproteinase; Zymography; Kidney; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002571629,0.0001193263,0.0002071773,0.0001828261,0.0002169534,0.00005167448,0.0002454378,0.0001213087,0.00001195578],"category_scores_gemma":[0.0004954627,0.0000755232,0.0001235351,0.0001910149,0.0001123239,0.00003201906,0.0001078473,0.0005140477,0.000001029207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003234126,"about_ca_system_score_gemma":0.0001670367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008116315,"about_ca_topic_score_gemma":0.00001354264,"domain_scores_codex":[0.9979412,0.0007236614,0.0002121432,0.0001947473,0.0006592986,0.0002689799],"domain_scores_gemma":[0.99909,0.00003455014,0.0001302344,0.0002664306,0.0003391859,0.0001396022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001066692,0.0002218862,0.003435228,0.00001639268,0.0002299977,0.0006105195,0.00007327354,9.558831e-7,0.99288,0.000007393011,0.002173881,0.0002438102],"study_design_scores_gemma":[0.003034117,0.002419095,0.03629528,0.0002423977,0.00005631476,0.0006518447,0.00008827618,0.0001360369,0.9545481,0.0002705828,0.002059251,0.0001987701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981342,0.0009343904,0.0003118459,0.000312475,0.00002632893,0.0002202253,0.000002768364,0.000002634207,0.00005512051],"genre_scores_gemma":[0.999025,0.0003172371,0.0001187154,0.0002692844,0.0001527885,0.00001379673,0.000008913284,0.00001450481,0.00007972153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03833196,"threshold_uncertainty_score":0.3079747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02768066558984181,"score_gpt":0.2799708019374376,"score_spread":0.2522901363475957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}