{"id":"W1989061093","doi":"10.1073/pnas.1321114111","title":"Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":288,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; University of California, San Diego; National Institutes of Health","keywords":"Mitophagy; Mitochondrial fission; DNM1L; Mitochondrion; Biology; Cell biology; Parkin; Apoptosis; Hepatitis C virus; Virology; Autophagy; Virus; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003983707,0.00007699095,0.0001071538,0.00006794209,0.0001432578,0.00001529247,0.0002964049,0.0000961,0.000008336327],"category_scores_gemma":[0.0007761558,0.00005344566,0.00005571616,0.0001859747,0.0003295569,0.00001551094,0.0001198738,0.00006164902,0.000001385905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006257354,"about_ca_system_score_gemma":0.000014185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001483099,"about_ca_topic_score_gemma":5.408236e-7,"domain_scores_codex":[0.9990939,0.0000118609,0.0001786418,0.0002629426,0.0003423811,0.0001102034],"domain_scores_gemma":[0.999626,0.00002186869,0.0001533985,0.000009762314,0.0001409184,0.00004807271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004634172,0.00001243743,0.002912521,0.00001302194,0.000005223574,6.925607e-10,0.00007204423,0.00001314887,0.9936049,0.0009818915,0.001631131,0.000707361],"study_design_scores_gemma":[0.0001817208,0.0002718522,0.005860495,0.00002870872,0.00000817896,0.000005054997,0.00003009347,0.0001798039,0.9871261,0.001449929,0.004783539,0.00007459979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966256,0.00003719926,0.00002151865,0.001743486,0.00007851929,0.0001505984,0.00001186904,0.000003625063,0.001327603],"genre_scores_gemma":[0.9943888,0.00006186312,0.004440334,0.0005640958,0.0002146,0.00001016127,5.114881e-7,0.00000330847,0.0003163719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006478853,"threshold_uncertainty_score":0.2179451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02389210525057394,"score_gpt":0.2715259443198341,"score_spread":0.2476338390692602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}