{"id":"W1989073386","doi":"10.1016/j.jconrel.2003.10.024","title":"Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes","year":2003,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Liposome; Biodistribution; Chemistry; Ethylene glycol; Methacrylic acid; Drug carrier; PEG ratio; Phospholipid; Chromatography; Pharmacokinetics; PEGylation; Pharmacology; Copolymer; Polyethylene glycol; Biochemistry; Drug delivery; In vitro; Membrane; Organic chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003737535,0.0002671235,0.0001784621,0.0001351554,0.0001166048,0.0003099754,0.0002797758,0.0003240328,0.0005853458],"category_scores_gemma":[0.0002869451,0.0001846042,0.0001888606,0.00007900548,0.0002333742,0.0005082684,0.000298071,0.0004217467,0.0002411537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004161557,"about_ca_system_score_gemma":0.00023193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003447573,"about_ca_topic_score_gemma":0.0004388512,"domain_scores_codex":[0.9998837,0.00001609726,0.000009535182,0.00002975342,0.00002984886,0.00003116069],"domain_scores_gemma":[0.9998943,0.00001851093,0.00003441843,0.00001296785,0.00001815151,0.00002173212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002003774,0.00002169391,0.0001026439,0.0000367565,0.000004753327,0.00004161575,0.00002902453,0.0001056173,0.9965922,0.0003052198,0.00008920401,0.002470958],"study_design_scores_gemma":[0.00003899934,0.0001323174,0.0007474103,0.000003447384,0.000009918183,0.0001571705,0.000007293943,0.0005812306,0.9965187,0.00006541114,0.001732549,0.000005657438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813827,0.002976856,0.01314308,0.0002185653,0.00004450595,0.00005450082,0.0002626972,0.0001876412,0.001729582],"genre_scores_gemma":[0.99182,0.0005661554,0.003644646,0.00006957637,0.00001076382,0.00002467992,0.00027496,0.00003713154,0.003552143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005853458,"threshold_uncertainty_score":0.003019452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007075365425198352,"score_gpt":0.2213269756935599,"score_spread":0.2142516102683615,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}