{"id":"W1989089334","doi":"10.1016/j.febslet.2009.12.010","title":"Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction","year":2009,"lang":"en","type":"review","venue":"FEBS Letters","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":278,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Alzheimer Society; Alberta Heritage Foundation for Medical Research; Huntington Society of Canada","keywords":"Sphingolipid; Sphingomyelin; Ceramide; Membrane; Cell biology; Function (biology); Nervous system; Biology; Cell membrane; Biochemistry; Chemistry; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002658815,0.0002415276,0.0005844455,0.0001023794,0.00005441936,0.00002609291,0.000118869,0.0002263493,0.000001081088],"category_scores_gemma":[0.00003897532,0.0001700815,0.0001463744,0.0001539406,0.00006506753,0.000004994148,0.00007410055,0.0001643882,5.683175e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001705825,"about_ca_system_score_gemma":0.00003235675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004558691,"about_ca_topic_score_gemma":0.00001290652,"domain_scores_codex":[0.9988849,0.0001407067,0.0003537789,0.0003404641,0.0001109104,0.0001692228],"domain_scores_gemma":[0.9994097,0.00001960366,0.0002306484,0.0002855419,0.00001733024,0.00003720106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001307351,0.00005785385,0.0005284846,0.0390037,0.0003402018,0.00001150407,0.000145426,0.00008328294,0.1210629,0.0004223848,0.00128686,0.8369266],"study_design_scores_gemma":[0.001040213,0.0001381776,0.002411969,0.008814477,0.001085834,0.0002185899,0.00009930503,0.00002055217,0.002355987,0.00001069545,0.9831551,0.0006490884],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06031458,0.9386457,0.00008461018,0.00004871589,0.0004972324,0.0003332122,0.000008459725,0.00000955485,0.00005794082],"genre_scores_gemma":[0.04273283,0.9559479,0.00004083343,0.0004174571,0.000724701,0.00002381545,0.00004308356,0.00003376453,0.00003560148],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9818683,"threshold_uncertainty_score":0.6935722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090560809561444,"score_gpt":0.228097271023628,"score_spread":0.2171916629280136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}