{"id":"W1989194287","doi":"10.1016/j.chom.2014.01.012","title":"From Arrest to Escape: HIV-1 Vpr Cuts a Deal","year":2014,"lang":"en","type":"letter","venue":"Cell Host & Microbe","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Endonuclease; Regulator; Cell biology; Innate immune system; Human immunodeficiency virus (HIV); Master regulator; Cell cycle checkpoint; Suppressor; Mechanism (biology); Cell; Cell cycle; Immune system; Virology; DNA; Genetics; Physics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004108934,0.001042057,0.0017563,0.0006345913,0.003638411,0.006617514,0.001912682,0.04536971,0.009675441],"category_scores_gemma":[0.01518418,0.0007643405,0.001280486,0.0003926782,0.006380556,0.009731108,0.003867289,0.05589478,0.006857975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004407867,"about_ca_system_score_gemma":0.00292262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001387729,"about_ca_topic_score_gemma":0.002732398,"domain_scores_codex":[0.9974457,0.0006363331,0.0001950238,0.0003530713,0.0008454887,0.0005243809],"domain_scores_gemma":[0.9952017,0.002739217,0.0002797721,0.0002981526,0.0005335077,0.0009476082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001387537,0.00004259954,0.0002289041,0.00008079271,0.00002826295,0.001551824,0.0001130106,0.00009797563,0.0005483653,0.01326868,0.9534247,0.03047617],"study_design_scores_gemma":[0.0002210238,0.0001375869,0.0004649534,0.0002892285,0.00003456945,0.002743091,0.00042801,0.0003910799,0.0006113189,0.05406896,0.9405471,0.00006310049],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0005153596,0.007867836,0.0002622353,0.9707578,0.01686962,0.00000973002,0.00001820147,0.00005765712,0.003641513],"genre_scores_gemma":[0.007772821,0.005548734,0.0003727797,0.9237777,0.05261417,0.00003190091,0.00002255976,0.00003883913,0.009820557],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04536971,"threshold_uncertainty_score":0.03236759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01122149844963977,"score_gpt":0.2381363298496653,"score_spread":0.2269148314000256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}