{"id":"W1989244555","doi":"10.1152/ajprenal.00062.2011","title":"Activity of the Ste20-like kinase, SLK, is enhanced by homodimerization","year":2011,"lang":"en","type":"article","venue":"American Journal of Physiology-Renal Physiology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Kinase; Cell biology; Fusion protein; p38 mitogen-activated protein kinases; Protein kinase A; Chemistry; Protein kinase domain; ASK1; Cyclin-dependent kinase 2; Mitogen-activated protein kinase kinase; Molecular biology; Biochemistry; Biology; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001373252,0.0002582436,0.0001875242,0.0001755833,0.0001092394,0.0002421056,0.0001031973,0.0001641133,0.0008980245],"category_scores_gemma":[0.0001181444,0.0001072559,0.0002085597,0.0001209369,0.000169687,0.0001782123,0.000193248,0.0002984079,0.0003237379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004380679,"about_ca_system_score_gemma":0.0001597259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002922913,"about_ca_topic_score_gemma":0.0003411516,"domain_scores_codex":[0.999859,0.0000249198,0.0000136254,0.00003192396,0.00003241197,0.00003815408],"domain_scores_gemma":[0.9999228,0.00001120849,0.00002350991,0.00001047969,0.000005856366,0.0000261737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009645552,0.00001501168,0.0003196336,0.00001904849,0.000003471056,0.00002090871,0.000008916123,0.00004635332,0.9988734,0.00007177454,0.00001456993,0.0005103682],"study_design_scores_gemma":[0.00001694802,0.0001161169,0.009357772,0.000004608811,0.00001154066,0.0003234797,0.00002165472,0.001728863,0.9870657,0.00008334324,0.001266042,0.000003944283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981635,0.0005905922,0.0006833175,0.00004207495,0.000006355828,0.000004234677,0.00008177955,0.00001981876,0.0004083666],"genre_scores_gemma":[0.998666,0.0002271792,0.0003986968,0.00001450297,0.000003072372,0.000006053047,0.0001914455,0.000005188107,0.0004877333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008980245,"threshold_uncertainty_score":0.003178418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006173672183803366,"score_gpt":0.2161389370728349,"score_spread":0.2099652648890316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}