{"id":"W1989247444","doi":"10.1001/jama.2008.758","title":"Clinical Equivalence of Generic and Brand-Name Drugs Used in Cardiovascular Disease","year":2008,"lang":"en","type":"review","venue":"JAMA","topic":"Pharmaceutical Economics and Policy","field":"Economics, Econometrics and Finance","cited_by":430,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Agency for Healthcare Research and Quality","keywords":"Medicine; Randomized controlled trial; Jadad scale; Medical prescription; Bioequivalence; Generic drug; Brand names; Clinical trial; MEDLINE; Context (archaeology); Drug; Internal medicine; Pharmacology; Advertising","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1254313,0.001344732,0.007954586,0.01654962,0.001133307,0.007359863,0.002619462,0.004680176,0.003860711],"category_scores_gemma":[0.4993652,0.001107092,0.006227613,0.01385206,0.003461264,0.006264337,0.001901196,0.002545943,0.0004771988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003774816,"about_ca_system_score_gemma":0.008450656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001143556,"about_ca_topic_score_gemma":0.001990357,"domain_scores_codex":[0.7768177,0.09730595,0.0849719,0.007793874,0.03212457,0.0009859579],"domain_scores_gemma":[0.2919272,0.5383238,0.129632,0.008226328,0.03004456,0.001846145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.006008819,0.0001557521,0.01865782,0.7898102,0.03941024,0.0004583082,0.001081774,0.0003172372,0.001303798,0.002643442,0.01247003,0.1276826],"study_design_scores_gemma":[0.01121753,0.003235659,0.0706276,0.678683,0.1519384,0.002341548,0.001674271,0.0007975145,0.00281697,0.01135055,0.06504813,0.0002688542],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008632023,0.9735475,0.001029965,0.006687734,0.005721916,0.0008107287,0.0007955013,0.0000250434,0.002749599],"genre_scores_gemma":[0.2963743,0.6464737,0.01337502,0.0160153,0.02242255,0.002878314,0.001670346,0.00007314329,0.0007172088],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1254313,"threshold_uncertainty_score":0.6633523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1798119531198471,"score_gpt":0.3666103435232169,"score_spread":0.1867983904033698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}