{"id":"W1989251035","doi":"10.1016/j.molbiopara.2009.12.008","title":"Biochemical and biophysical characterisation of DBL1α1-varO, the rosetting domain of PfEMP1 from the VarO line of Plasmodium falciparum","year":2010,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Malaria Research and Control","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Agence Nationale de la Recherche; Institut national de la recherche scientifique","keywords":"Biology; Pichia pastoris; Plasmodium falciparum; Recombinant DNA; Biochemistry; Binding domain; Fusion protein; Binding site; Molecular biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001735814,0.0002487696,0.000150994,0.0001239417,0.0002237538,0.000260488,0.0002774296,0.0002345277,0.0005660629],"category_scores_gemma":[0.0003405068,0.0001370309,0.0001755188,0.0001921799,0.0002097955,0.0002313626,0.0001260753,0.0006353756,0.0002801196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003092053,"about_ca_system_score_gemma":0.000116858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001130638,"about_ca_topic_score_gemma":0.001336337,"domain_scores_codex":[0.9999154,0.00001495789,0.000009914664,0.00001921729,0.00002077469,0.00001986195],"domain_scores_gemma":[0.9998689,0.0000378652,0.00002592462,0.00001643443,0.00002369636,0.00002725721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001079292,0.00002567341,0.0004632076,0.00002590798,0.000004403826,0.0000914703,0.00002791739,0.0001425649,0.9984111,0.0001150652,0.00006903198,0.0005157897],"study_design_scores_gemma":[0.00002376795,0.0001163645,0.019358,0.000008745257,0.00001852367,0.001230142,0.0001007649,0.003334431,0.969609,0.0001230769,0.006059954,0.00001723104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961728,0.0006529519,0.001489528,0.0001977305,0.00002555661,0.00001051607,0.0007370371,0.00001360578,0.0007001889],"genre_scores_gemma":[0.9920617,0.0004332293,0.002018994,0.0001199787,0.00001097959,0.00001310904,0.003461534,0.00001745214,0.001862989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001130638,"threshold_uncertainty_score":0.002248108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007134626555942941,"score_gpt":0.2786027342901424,"score_spread":0.2714681077341994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}