{"id":"W1989251035","doi":"10.1016/j.molbiopara.2009.12.008","title":"Biochemical and biophysical characterisation of DBL1α1-varO, the rosetting domain of PfEMP1 from the VarO line of Plasmodium falciparum","year":2010,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Malaria Research and Control","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Agence Nationale de la Recherche; Institut national de la recherche scientifique","keywords":"Biology; Pichia pastoris; Plasmodium falciparum; Recombinant DNA; Biochemistry; Binding domain; Fusion protein; Binding site; Molecular biology; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002147288,0.00013353,0.0004084338,0.00003259423,0.00003506377,0.00000632567,0.0001529349,0.0002255597,0.00002060078],"category_scores_gemma":[0.0003537598,0.00007653006,0.0000981073,0.0001078231,0.0008557497,0.00001426236,0.0000915907,0.0003815279,8.299345e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003727228,"about_ca_system_score_gemma":0.00004571594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008574873,"about_ca_topic_score_gemma":0.000002280575,"domain_scores_codex":[0.9989002,0.00009202554,0.0003376114,0.0002439678,0.0002127466,0.0002134758],"domain_scores_gemma":[0.9990171,0.0003331163,0.0001446221,0.0003117351,0.00009333315,0.0001000979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006715233,0.0001384782,0.005937294,0.00004857067,0.0001031667,0.000006765548,0.0001297996,6.765238e-8,0.9913169,0.00108042,0.0001067426,0.0004603062],"study_design_scores_gemma":[0.001219246,0.0002241246,0.04234776,0.00002644177,0.00009953901,0.00003175388,0.00008065725,0.0002817728,0.9548913,0.0006637582,0.0000662103,0.00006750588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924702,0.0003417046,0.0004031477,0.006320945,0.0000446023,0.0002680761,0.0000533087,0.000006151343,0.00009188299],"genre_scores_gemma":[0.9990752,0.0000203793,0.0004749384,0.0002230027,0.0001093536,0.00001332607,0.00007116993,0.000008873642,0.000003782855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03642563,"threshold_uncertainty_score":0.3153045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007134626555942941,"score_gpt":0.2786027342901424,"score_spread":0.2714681077341994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}