{"id":"W1989301770","doi":"10.1111/j.1399-0004.2012.01868.x","title":"Whole‐genome sequencing and the physician","year":2012,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Genomics and Rare Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill Genome Centre; McGill University; McGill University Health Centre","funders":"","keywords":"Library science; Genomics; Precision medicine; Genetics; Computer science; Biology; Genome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008532552,0.0004992057,0.0006551854,0.001291865,0.0009408596,0.002540097,0.0008997614,0.005790524,0.01140656],"category_scores_gemma":[0.01805267,0.0004473649,0.0004200457,0.0005935092,0.003706079,0.004169262,0.002321577,0.007578532,0.00462675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001559304,"about_ca_system_score_gemma":0.002791255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001820224,"about_ca_topic_score_gemma":0.002395793,"domain_scores_codex":[0.997488,0.001390154,0.0001308532,0.0002679133,0.0005743174,0.0001487994],"domain_scores_gemma":[0.9862058,0.007611142,0.0004647583,0.00137964,0.001963446,0.002375306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002501877,0.0001581343,0.006976989,0.0002273063,0.00007698241,0.00217235,0.0004186513,0.0006132231,0.003284019,0.05747364,0.5797078,0.3486407],"study_design_scores_gemma":[0.00009356728,0.0001494061,0.004978663,0.0005225621,0.00004409154,0.005326998,0.0006843224,0.0009270186,0.001129354,0.2095964,0.7764891,0.00005835935],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.005616968,0.04430088,0.01628566,0.8881799,0.009536088,0.0000311016,0.000329353,0.0005766858,0.03514334],"genre_scores_gemma":[0.1581935,0.08465046,0.03926337,0.618241,0.04980556,0.0001033134,0.0006234657,0.0005583761,0.04856106],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01140656,"threshold_uncertainty_score":0.04512501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03384488496767487,"score_gpt":0.3176150832159452,"score_spread":0.2837701982482703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}