{"id":"W1989334647","doi":"10.1016/j.mod.2008.11.007","title":"Requirement of Wnt/β-catenin signaling in pronephric kidney development","year":2008,"lang":"en","type":"article","venue":"Mechanisms of Development","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; March of Dimes Foundation; National Cancer Institute; National Institutes of Health; British Sedimentological Research Group","keywords":"Pronephros; Biology; Wnt signaling pathway; Xenopus; Kidney development; Cell biology; Zebrafish; Somite; WNT4; Beta-catenin; Nephron; Internal medicine; Endocrinology; Kidney; Signal transduction; Embryogenesis; Genetics; Embryo; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002651592,0.0001678659,0.0002311441,0.0001192265,0.00005611765,0.000002152996,0.0001895112,0.0001323457,0.00002573662],"category_scores_gemma":[0.00002153891,0.0001481516,0.00005026284,0.0001609363,0.00004451313,0.000003753131,0.0001131766,0.00007098715,0.000006144696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007146056,"about_ca_system_score_gemma":0.0009162648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001244454,"about_ca_topic_score_gemma":0.000006877931,"domain_scores_codex":[0.9985566,0.00002743238,0.0005904048,0.0002809963,0.0002907866,0.0002537837],"domain_scores_gemma":[0.9995019,0.000003497714,0.0001911784,0.0001208506,0.00008813669,0.00009441827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008024406,0.0001227026,0.0003987181,0.00008610803,0.00009303445,0.000008854381,0.0006529368,0.0001884804,0.9953094,0.0001497181,0.0001399416,0.002769845],"study_design_scores_gemma":[0.0006777683,0.000123302,0.0009856611,0.0001550229,0.000005404056,0.00001079955,0.00008017898,0.000005104172,0.9947459,0.0001250991,0.002890665,0.0001950992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919626,0.0003009555,0.006809045,0.00005630885,0.0001292562,0.0002730998,0.000001719653,0.000007596839,0.0004594768],"genre_scores_gemma":[0.9564954,0.0001234382,0.04266278,0.00008703099,0.0000131685,0.00005031952,0.00004950198,0.00001631752,0.0005020502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03585373,"threshold_uncertainty_score":0.6041448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01485569688865018,"score_gpt":0.2180558607310267,"score_spread":0.2032001638423765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}