{"id":"W1989351245","doi":"10.1055/s-2009-1216497","title":"Isolation of Pyrrolizidine Alkaloid Isomers from Symphytum Species by Semi-Preparative Chiral Chromatography","year":2009,"lang":"en","type":"article","venue":"Planta Medica","topic":"Plant Toxicity and Pharmacological Properties","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; Agricultural Research Service; University of British Columbia; University of Illinois at Urbana-Champaign; Chinese Academy of Sciences; Kurukshetra University; University of Illinois at Chicago; National Oceanic and Atmospheric Administration; U.S. Food and Drug Administration; National Science Foundation of Sri Lanka; University of Colombo; U.S. Department of Agriculture; Western Carolina University; International Science Council; National Center for Complementary and Alternative Medicine; China Academy of Traditional Chinese Medicine; National Institutes of Health; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Hong Kong Polytechnic University; National Science Foundation; Deutsche Krebshilfe; National Natural Science Foundation of China; Tata Trusts; University Grants Commission; Wake Forest University","keywords":"Pyrrolizidine; Boraginaceae; Pyrrolizidine alkaloid; Chromatography; Alkaloid; Chemistry; High-performance liquid chromatography; Silica gel; Organic chemistry; Stereochemistry; Botany; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008529259,0.0001480385,0.0002094274,0.00003399669,0.00006042937,0.000008638848,0.0001896259,0.0001532067,0.0001942473],"category_scores_gemma":[0.00003526081,0.0001167473,0.00007786245,0.00006561632,0.000138502,0.000007621054,0.00003460234,0.0001026018,0.000009662272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005833125,"about_ca_system_score_gemma":0.00002585283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002239938,"about_ca_topic_score_gemma":0.000006104317,"domain_scores_codex":[0.9990982,0.00006104634,0.0002221948,0.0002474511,0.00017758,0.000193572],"domain_scores_gemma":[0.9996163,0.00002814362,0.0001069819,0.0001287567,0.00002314126,0.00009670016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003172535,0.00009626753,0.000768403,0.000007134659,0.00007637667,0.000003409858,0.0001250247,0.000007525381,0.9462577,0.00002434407,0.05207228,0.0002442926],"study_design_scores_gemma":[0.0006410981,0.0005953262,0.00368759,0.00003031082,0.00003901012,0.000009715674,0.00008336087,0.0002759174,0.9620692,0.0002057041,0.03216838,0.0001944368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871997,0.002306218,0.0005711282,0.0004028458,0.0001438143,0.0001238236,0.0007297092,0.00002319579,0.008499533],"genre_scores_gemma":[0.9953625,0.001775417,0.0001272441,0.0008440422,0.0002060413,0.000004582153,0.001380651,0.000005301513,0.000294221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0199039,"threshold_uncertainty_score":0.4760817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153043470333076,"score_gpt":0.2381432662329738,"score_spread":0.226612831529643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}