{"id":"W1989351245","doi":"10.1055/s-2009-1216497","title":"Isolation of Pyrrolizidine Alkaloid Isomers from Symphytum Species by Semi-Preparative Chiral Chromatography","year":2009,"lang":"en","type":"article","venue":"Planta Medica","topic":"Plant Toxicity and Pharmacological Properties","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Drug Abuse; Agricultural Research Service; University of British Columbia; University of Illinois at Urbana-Champaign; Chinese Academy of Sciences; Kurukshetra University; University of Illinois at Chicago; National Oceanic and Atmospheric Administration; U.S. Food and Drug Administration; National Science Foundation of Sri Lanka; University of Colombo; U.S. Department of Agriculture; Western Carolina University; International Science Council; National Center for Complementary and Alternative Medicine; China Academy of Traditional Chinese Medicine; National Institutes of Health; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Hong Kong Polytechnic University; National Science Foundation; Deutsche Krebshilfe; National Natural Science Foundation of China; Tata Trusts; University Grants Commission; Wake Forest University","keywords":"Pyrrolizidine; Boraginaceae; Pyrrolizidine alkaloid; Chromatography; Alkaloid; Chemistry; High-performance liquid chromatography; Silica gel; Organic chemistry; Stereochemistry; Botany; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003057921,0.0005199381,0.0005181422,0.0008826859,0.000460235,0.0003419749,0.0002888589,0.0003239101,0.004739929],"category_scores_gemma":[0.0004117251,0.0002372518,0.0003711679,0.0004976554,0.0003029694,0.0003518922,0.0003504468,0.0006510026,0.001678135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002020788,"about_ca_system_score_gemma":0.0005894739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008652775,"about_ca_topic_score_gemma":0.002154457,"domain_scores_codex":[0.999837,0.00004220651,0.00001160428,0.00003477035,0.00003826607,0.00003609343],"domain_scores_gemma":[0.9998323,0.00003743339,0.00003216714,0.00002688885,0.00003615086,0.00003507184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008133041,0.0004277908,0.0002792824,0.0002494149,0.00003514201,0.0003528912,0.00007109002,0.0002329516,0.9635007,0.0007126363,0.0004409618,0.03288374],"study_design_scores_gemma":[0.0009689321,0.009564263,0.009741858,0.00009190894,0.000205835,0.002609239,0.0001944755,0.002942865,0.9422303,0.0009026568,0.0304759,0.00007166879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8687666,0.01251047,0.08493083,0.001353411,0.0002544661,0.004213374,0.003542445,0.0006657675,0.02376273],"genre_scores_gemma":[0.9168847,0.008973951,0.05472806,0.0009254038,0.0002028563,0.0006778898,0.002144793,0.0001394132,0.01532289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004739929,"threshold_uncertainty_score":0.01585668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153043470333076,"score_gpt":0.2381432662329738,"score_spread":0.226612831529643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}