{"id":"W1989353916","doi":"10.3899/jrheum.100398","title":"High DNA Oxidative Damage in Systemic Sclerosis","year":2010,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Internal medicine; Pathogenesis; Lipid peroxidation; DNA damage; 8-Hydroxy-2'-deoxyguanosine; Deoxyguanosine; DLCO; Reactive oxygen species; Urinary system; Oxidative stress; Biomarker; Endocrinology; Gastroenterology; Pathology; DNA oxidation; Diffusing capacity; Oxidative damage; Lung; Biochemistry; DNA; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002977159,0.0003329476,0.000269074,0.001294331,0.0002273841,0.0002945921,0.0001449551,0.0003349284,0.003056766],"category_scores_gemma":[0.0007880038,0.0001208108,0.0001049583,0.0007117298,0.0002679624,0.0001530433,0.0002594933,0.000236545,0.000233472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001820154,"about_ca_system_score_gemma":0.0001384534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004049134,"about_ca_topic_score_gemma":0.0003529872,"domain_scores_codex":[0.9997693,0.00004598163,0.00002588157,0.00005287696,0.00008673264,0.00001929096],"domain_scores_gemma":[0.9992853,0.0001097797,0.0004062747,0.00002073069,0.00008745176,0.00009045162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001033246,0.0001508898,0.9125718,0.0003425698,0.0001759123,0.001540671,0.000216634,0.0002097253,0.06207573,0.00009043636,0.0001682726,0.02142414],"study_design_scores_gemma":[0.00002503817,0.0005420056,0.988871,0.00003834022,0.00005847049,0.005943532,0.00007050217,0.0002275827,0.00355212,0.0001345579,0.0005314158,0.000005406628],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99624,0.002959331,0.0002006377,0.00004183713,0.000005600486,0.00000819606,0.00008041641,0.00002328241,0.0004405899],"genre_scores_gemma":[0.9990619,0.0004930776,0.0001487417,0.00001665654,0.00001469143,0.000005760767,0.00007180402,0.000001252462,0.000186099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003056766,"threshold_uncertainty_score":0.01022589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566150115242585,"score_gpt":0.2443604778511638,"score_spread":0.2286989766987379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}