{"id":"W1989354370","doi":"10.1038/modpathol.2009.89","title":"Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 mutation carriers","year":2009,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":214,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"University Health Network; Canary Foundation","keywords":"BRCA mutation; Serous carcinoma; Serous fluid; Fallopian tube; Fallopian tube cancer; Medicine; Pathology; Ovarian cancer; Cancer; Lynch syndrome; Carcinoma; Immunostaining; Malignancy; Germline mutation; Oncology; Internal medicine; Mutation; Immunohistochemistry; Biology; Gynecology; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003636324,0.0004000568,0.0003741594,0.002842487,0.0007329394,0.0009630821,0.0004420383,0.000696686,0.004710556],"category_scores_gemma":[0.00327714,0.0003245163,0.0002755396,0.0005955424,0.0004458833,0.0005491716,0.0005013606,0.0003135522,0.0004864337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002284888,"about_ca_system_score_gemma":0.0003010087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001188791,"about_ca_topic_score_gemma":0.0009352044,"domain_scores_codex":[0.9997862,0.000044128,0.00002359266,0.00003532463,0.00004151266,0.00006934402],"domain_scores_gemma":[0.9991441,0.0003389255,0.0001613794,0.00004946272,0.00008715427,0.0002188972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00252723,0.00008946603,0.9200324,0.00006253322,0.00002480317,0.04711951,0.0006095947,0.0001740501,0.02042337,0.0002983108,0.0002765085,0.008362214],"study_design_scores_gemma":[0.00008327128,0.0009313302,0.838432,0.00004800504,0.0001476073,0.1392185,0.002366266,0.00171367,0.01435203,0.0007480715,0.001927811,0.00003147969],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986539,0.0002830705,0.0001058998,0.00003290463,0.00001130792,0.00001041158,0.00005596856,0.00001150001,0.0008350476],"genre_scores_gemma":[0.9992703,0.0001162224,0.0002347417,0.00001643286,0.00001335022,0.000005298206,0.0000669854,0.000004826045,0.0002718594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004710556,"threshold_uncertainty_score":0.0157584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01260611106007934,"score_gpt":0.2885385424456439,"score_spread":0.2759324313855646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}