{"id":"W1989355680","doi":"10.1016/j.micres.2006.08.002","title":"Inhibitory activity against papain, a CA1 cysteine peptidase, in Saccharomycetaceae","year":2006,"lang":"en","type":"article","venue":"Microbiological Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Centre National de la Recherche Scientifique","keywords":"Papain; Yeast; Biology; Cysteine; Biochemistry; Enzyme; Intracellular; Cysteine Proteinase Inhibitors; Inhibitory postsynaptic potential; Saccharomyces cerevisiae; Biological activity; Proteases; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001518492,0.0002116049,0.0002263388,0.0001209665,0.0001329764,0.00004284829,0.0004273372,0.000377092,0.00005526444],"category_scores_gemma":[0.0006871357,0.0001782511,0.0001256928,0.0003495211,0.000410953,0.000004561849,0.0004605905,0.0005197602,0.0001070608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001022745,"about_ca_system_score_gemma":0.000158825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001217839,"about_ca_topic_score_gemma":0.0001428312,"domain_scores_codex":[0.9972471,0.0007540996,0.0002658311,0.0007246691,0.0002170688,0.0007912128],"domain_scores_gemma":[0.9990175,0.0001318474,0.00004770699,0.0004916246,0.0001780874,0.0001332165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002497498,0.0003791084,0.009471002,0.00002348409,0.000009531159,0.00007675778,0.000007187494,0.00006692034,0.9779523,0.00002999216,0.01090775,0.000826207],"study_design_scores_gemma":[0.0009998091,0.0004676825,0.01362736,0.00005098682,0.000002588867,0.00001036435,0.00003107469,0.00001945145,0.9605349,0.0001644745,0.02379409,0.0002972767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958262,0.001001983,0.00004349278,0.0002361519,0.00006042073,0.0003981039,0.00007508886,0.00002989815,0.002328683],"genre_scores_gemma":[0.9975203,0.0000414351,0.0001526719,0.0001502691,0.0003643496,0.00008828833,0.0002487778,0.00002395594,0.001409958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01741747,"threshold_uncertainty_score":0.7268869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03747997602504598,"score_gpt":0.3265590289971767,"score_spread":0.2890790529721307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}