{"id":"W1989371089","doi":"10.4161/nucl.1.2.11113","title":"Dosage effect of zero to three functional LBR-genes in vivo and in vitro","year":2010,"lang":"en","type":"article","venue":"Nucleus","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Deutsche Forschungsgemeinschaft","keywords":"Lamin; Granulopoiesis; Biology; Molecular biology; Gene; Nuclear lamina; In vivo; Cell biology; Nuclear protein; Genetics; Haematopoiesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002905135,0.0003882232,0.0002583461,0.0002850099,0.0001172104,0.000348246,0.000270834,0.0003054464,0.001753808],"category_scores_gemma":[0.0003288118,0.0002045244,0.0002221631,0.0001568153,0.0004193118,0.000142808,0.0003204339,0.0005028589,0.0002985075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003726061,"about_ca_system_score_gemma":0.000155823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009678358,"about_ca_topic_score_gemma":0.001268744,"domain_scores_codex":[0.9995241,0.000174678,0.0000665339,0.0001019195,0.00008498307,0.00004783828],"domain_scores_gemma":[0.9994517,0.0003040909,0.00007204088,0.00009679361,0.00001813954,0.00005726639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002110805,0.00004877354,0.0002863577,0.00003497209,0.00001159636,0.00004267969,0.00003059494,0.0001695124,0.9977265,0.0001308788,0.00003668442,0.001270393],"study_design_scores_gemma":[0.00001599344,0.0005094655,0.003121591,0.000004394594,0.00002605809,0.0001483401,0.00002513528,0.0009506131,0.994119,0.000048764,0.001023469,0.000007113525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950553,0.001261769,0.001944742,0.00005858012,0.00002883435,0.00002643013,0.0004927889,0.00005434656,0.001077172],"genre_scores_gemma":[0.9943365,0.0006106761,0.002024377,0.00003440801,0.000009822961,0.00003771834,0.0008859406,0.00003698939,0.002023476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001753808,"threshold_uncertainty_score":0.005867064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003584389942616996,"score_gpt":0.2057295589790346,"score_spread":0.2021451690364175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}