{"id":"W1989466967","doi":"10.1007/s10549-010-1322-0","title":"A randomized, placebo-controlled trial (NCIC CTG MAP.2) examining the effects of exemestane on mammographic breast density, bone density, markers of bone metabolism and serum lipid levels in postmenopausal women","year":2011,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Medical Imaging Techniques and Applications","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Notre-Dame; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Pfizer","keywords":"Medicine; Bone remodeling; Bone mineral; Internal medicine; Femoral neck; Endocrinology; Exemestane; N-terminal telopeptide; Bone density; Placebo; Bone resorption; Breast cancer; Osteoporosis; Osteocalcin; Urology; Aromatase; Cancer; Alkaline phosphatase; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021059,0.0002537558,0.001326532,0.0004102804,0.0001110596,0.00001902085,0.00009204654,0.00009378838,0.0000684763],"category_scores_gemma":[0.0001278848,0.0001464402,0.0001008157,0.000353829,0.000818062,0.00004574589,0.000130661,0.0002828136,9.816677e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001447185,"about_ca_system_score_gemma":0.0002261081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003480467,"about_ca_topic_score_gemma":0.0001706615,"domain_scores_codex":[0.9974222,0.0005315007,0.0005162766,0.0004057505,0.000604507,0.0005197952],"domain_scores_gemma":[0.9979028,0.0009922513,0.0001753232,0.0004022984,0.0001946521,0.0003326654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9620852,0.001588287,0.002913567,0.0002576647,0.00066711,0.0001300206,0.0009293426,4.8933e-8,0.003710366,0.0005630765,0.00006553311,0.02708975],"study_design_scores_gemma":[0.8717782,0.003450641,0.1189377,0.0006837308,0.0004305289,0.0003772083,0.0002746653,0.00004984791,0.003028233,0.0008162858,0.00002169081,0.0001512811],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907096,0.001203131,0.00001207082,0.001691112,0.0000494596,0.006097128,0.00006163317,0.00002580883,0.0001500493],"genre_scores_gemma":[0.9944778,0.001767503,0.0002761177,0.00006003634,0.00009215115,0.003066096,0.000005878429,0.00002448847,0.0002299458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1160241,"threshold_uncertainty_score":0.597166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04163460295974158,"score_gpt":0.3285250110864677,"score_spread":0.2868904081267261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}