{"id":"W1989496984","doi":"10.1371/journal.pone.0083130","title":"Secreted hCLCA1 Is a Signaling Molecule That Activates Airway Macrophages","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Saskatchewan Health Research Foundation","keywords":"Cell biology; Inflammation; HEK 293 cells; Macrophage; Cytokine; Proinflammatory cytokine; Signal transduction; Mucus; Immunology; Biology; Cell culture; Chemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001477138,0.0003747451,0.0002931573,0.0002363557,0.0002025114,0.0003225869,0.0001257547,0.0004730852,0.002135623],"category_scores_gemma":[0.000171429,0.000115813,0.0003927697,0.0001556172,0.0002018921,0.0001956723,0.0002554405,0.0005267745,0.0004968934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002629143,"about_ca_system_score_gemma":0.0001526561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003358089,"about_ca_topic_score_gemma":0.000398386,"domain_scores_codex":[0.9998538,0.00002239929,0.000008533272,0.00003832631,0.00004542348,0.00003143965],"domain_scores_gemma":[0.9998955,0.00001977173,0.00002709104,0.000009249103,0.00001827874,0.00003016522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008008597,0.00001091371,0.0003808287,0.00006484595,0.000004923859,0.00009557734,0.00001084736,0.00003333679,0.9978608,0.00004938666,0.00009142896,0.001317052],"study_design_scores_gemma":[0.00007464496,0.0007636707,0.0219559,0.000035111,0.00003652143,0.002296273,0.0001109258,0.001506811,0.9571725,0.0001589099,0.01587226,0.00001650998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760336,0.01198487,0.006281529,0.0007688377,0.0001422411,0.0000919394,0.001746009,0.0002118323,0.00273903],"genre_scores_gemma":[0.9871441,0.002684197,0.00441525,0.0003137062,0.00009036953,0.00005676719,0.001981706,0.00002426258,0.003289745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002135623,"threshold_uncertainty_score":0.007144392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03309790292937802,"score_gpt":0.2373814428972099,"score_spread":0.2042835399678319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}