{"id":"W1989527639","doi":"10.1016/j.actbio.2014.06.008","title":"Colocation and role of polyphosphates and alkaline phosphatase in apatite biomineralization of elasmobranch tesserae","year":2014,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Bone health and treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Basic Energy Sciences; Feinberg School of Medicine; Leibniz-Gemeinschaft; Office of Science; Gottfried Wilhelm Leibniz Universität Hannover; Deutscher Akademischer Austauschdienst; Deutsche Forschungsgemeinschaft; University of Washington; Northwestern University; Argonne National Laboratory; U.S. Department of Energy","keywords":"Biomineralization; Mineralization (soil science); Alkaline phosphatase; Apatite; Endochondral ossification; Cartilage; Chemistry; Calcification; Hypophosphatasia; Biophysics; Anatomy; Biochemistry; Biology; Mineralogy; Enzyme; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001230351,0.00008760668,0.0002476388,0.00009649322,0.00001688534,0.000006564962,0.00001956439,0.0000692886,0.00002332451],"category_scores_gemma":[0.00004745838,0.00007377594,0.000009742912,0.0001374624,0.00005954134,0.00007455024,0.00001651961,0.00001184947,0.000001295354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001087628,"about_ca_system_score_gemma":0.00002122903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003152219,"about_ca_topic_score_gemma":0.00009556865,"domain_scores_codex":[0.999363,0.00002896563,0.0002976921,0.0001324122,0.00007181963,0.0001061311],"domain_scores_gemma":[0.9996053,0.00002083898,0.0001401051,0.0001179701,0.00004923767,0.0000665655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004219711,0.0001678034,0.2296285,0.0003594119,0.00001856013,7.898176e-7,0.0002025158,9.127638e-8,0.7657382,0.000498305,0.00006288578,0.002900968],"study_design_scores_gemma":[0.002462595,0.0003294408,0.3838224,0.0001245577,0.00003833979,0.000005717643,0.00001632883,0.0004365928,0.611942,0.0001813251,0.0005891492,0.00005158498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986017,0.0007068031,0.000007658537,0.0002333155,0.0001020705,0.0002625209,0.00005105415,0.00001082341,0.00002405206],"genre_scores_gemma":[0.9990011,0.0001900019,0.0004122468,0.00007035516,0.00001249774,0.00001255794,0.0002667636,0.000009338964,0.00002509716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1541939,"threshold_uncertainty_score":0.4765234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005516989472777866,"score_gpt":0.2458909420903935,"score_spread":0.2403739526176156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}