{"id":"W1989527639","doi":"10.1016/j.actbio.2014.06.008","title":"Colocation and role of polyphosphates and alkaline phosphatase in apatite biomineralization of elasmobranch tesserae","year":2014,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Bone health and treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Basic Energy Sciences; Feinberg School of Medicine; Leibniz-Gemeinschaft; Office of Science; Gottfried Wilhelm Leibniz Universität Hannover; Deutscher Akademischer Austauschdienst; Deutsche Forschungsgemeinschaft; University of Washington; Northwestern University; Argonne National Laboratory; U.S. Department of Energy","keywords":"Biomineralization; Mineralization (soil science); Alkaline phosphatase; Apatite; Endochondral ossification; Cartilage; Chemistry; Calcification; Hypophosphatasia; Biophysics; Anatomy; Biochemistry; Biology; Mineralogy; Enzyme; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001894286,0.0003266845,0.000148068,0.0005674241,0.0002524831,0.0003640715,0.000352055,0.0006189865,0.0005720352],"category_scores_gemma":[0.0002236442,0.0003339298,0.0002819722,0.0001363514,0.0006452786,0.0004920918,0.0003386125,0.0005017945,0.0002604371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000221233,"about_ca_system_score_gemma":0.0003285617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001518815,"about_ca_topic_score_gemma":0.002182667,"domain_scores_codex":[0.9998683,0.00001119696,0.000009108015,0.00004797383,0.00003208624,0.00003136745],"domain_scores_gemma":[0.9997752,0.00004264556,0.00006200691,0.00001739484,0.00004840423,0.00005434511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000449932,0.000005813451,0.0006789899,0.00003474877,0.000004125406,0.00006753012,0.00003682026,0.00003489931,0.997945,0.0001077277,0.00000613736,0.001033154],"study_design_scores_gemma":[0.00001445739,0.0002757008,0.04699174,0.00001175292,0.00002458999,0.0004679834,0.0002408331,0.0008550201,0.9495673,0.0001950546,0.001338272,0.00001726739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935485,0.001402965,0.002705786,0.00006283345,0.00001696548,0.00001923999,0.0001294344,0.00004421543,0.002070122],"genre_scores_gemma":[0.9916331,0.0005089889,0.004090597,0.00006692456,0.000011182,0.0000290708,0.0001478699,0.00002763341,0.003484556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001518815,"threshold_uncertainty_score":0.003019869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005516989472777866,"score_gpt":0.2458909420903935,"score_spread":0.2403739526176156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}