{"id":"W1989652867","doi":"10.1038/nsb1014","title":"Germline antibody recognition of distinct carbohydrate epitopes","year":2003,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria; Institute for Biological Sciences; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; University of Alberta; Austrian Science Fund; University of Ottawa; U.S. Department of Energy","keywords":"Epitope; Germline; Complementarity determining region; Biology; Immunogen; Antibody; Computational biology; Antigen; Genetics; Gene; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002282682,0.0002413671,0.0002046257,0.0001948011,0.0001805072,0.0005715085,0.0004443412,0.00043343,0.001659647],"category_scores_gemma":[0.0003628831,0.0001843652,0.0002296164,0.0001260263,0.0001872151,0.0002671204,0.0005577325,0.0008080024,0.0004684919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004977218,"about_ca_system_score_gemma":0.0001867341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005376452,"about_ca_topic_score_gemma":0.0008984327,"domain_scores_codex":[0.99979,0.00002191474,0.000007453606,0.00003949706,0.00004673763,0.0000943514],"domain_scores_gemma":[0.999797,0.00005597633,0.00002669395,0.00002761587,0.00004227959,0.00005042741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001007439,0.00003227757,0.0005938722,0.00001783851,0.000007454433,0.00008946356,0.00002964067,0.0001340756,0.9922463,0.001772944,0.00009316997,0.00488216],"study_design_scores_gemma":[0.00007935542,0.0003068976,0.009055962,0.0000157405,0.00003122338,0.001140203,0.00009476249,0.003970054,0.9789991,0.001344582,0.004948969,0.00001304594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906014,0.0004463834,0.004069873,0.00008049147,0.00003965529,0.000008939267,0.00003907722,0.00003580146,0.004678356],"genre_scores_gemma":[0.9969736,0.0001899737,0.001132669,0.00009378945,0.000008070084,0.000005496427,0.0001097268,0.00001388033,0.001472695],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001659647,"threshold_uncertainty_score":0.005552113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006952888692834327,"score_gpt":0.3275555254165037,"score_spread":0.3206026367236693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}