{"id":"W1989654480","doi":"10.1167/iovs.11-7989","title":"The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties","year":2011,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Ocular Oncology and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Retinoblastoma; Biology; Retinoblastoma protein; Molecular biology; Immunostaining; Embryonic stem cell; Cell; Immunohistochemistry; Cell cycle; Genetics; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0002913007,0.0002248948,0.0004022122,0.00009901753,0.0003184224,0.000008797539,0.0003489277,0.0001337331,0.0000637632],"category_scores_gemma":[0.0002393702,0.0001189624,0.00006911012,0.0005156925,0.01504235,0.0001001533,0.0001417166,0.0002686334,0.00001031166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007882651,"about_ca_system_score_gemma":0.0006825247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001380901,"about_ca_topic_score_gemma":0.000003292188,"domain_scores_codex":[0.9983599,0.0001418003,0.0003289953,0.0004041854,0.000384448,0.0003806414],"domain_scores_gemma":[0.9986745,0.00007780374,0.000312028,0.0003232787,0.0004427086,0.0001696617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001083829,0.0006373056,0.1516288,0.00004242926,0.0001120544,0.0001320622,0.001430768,1.349198e-7,0.8447936,0.00006543131,0.00002602743,0.00004749068],"study_design_scores_gemma":[0.0008205233,0.003153887,0.2961445,0.0000852806,0.00009126068,0.0003020514,0.0001707711,0.000007555203,0.698956,0.0001734673,0.00001022135,0.00008460393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970083,0.0003284866,5.657024e-7,0.000143574,0.0001215921,0.0005806797,0.000004053943,0.00002049529,0.001792251],"genre_scores_gemma":[0.9979274,0.000003474,0.001280762,0.00002412682,0.00001889972,0.00006495618,0.00000421018,0.00001433268,0.0006618928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1458377,"threshold_uncertainty_score":0.9876381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05426104612637696,"score_gpt":0.3085947395058696,"score_spread":0.2543336933794926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}