{"id":"W1989654480","doi":"10.1167/iovs.11-7989","title":"The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties","year":2011,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Ocular Oncology and Treatments","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Retinoblastoma; Biology; Retinoblastoma protein; Molecular biology; Immunostaining; Embryonic stem cell; Cell; Immunohistochemistry; Cell cycle; Genetics; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001632247,0.0005058983,0.0001864802,0.0007954111,0.0002692565,0.0002526912,0.0002482024,0.0003905748,0.001882209],"category_scores_gemma":[0.00009797572,0.0002432883,0.0002267846,0.0002978891,0.0003113538,0.0002330767,0.0001908448,0.0004263562,0.001675939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003387719,"about_ca_system_score_gemma":0.0002145121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001124091,"about_ca_topic_score_gemma":0.002214518,"domain_scores_codex":[0.9997917,0.0000147074,0.00002540337,0.00005194771,0.00007552754,0.000040694],"domain_scores_gemma":[0.9997057,0.00002773076,0.0001043774,0.00006278411,0.00003438429,0.00006490267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001123798,0.00002730384,0.0006946896,0.000023358,0.000004919762,0.0001264544,0.00003835038,0.00005821121,0.9975281,0.0002817342,0.00004726372,0.001057236],"study_design_scores_gemma":[0.00003049639,0.0005273137,0.0122955,0.00001439563,0.00002872413,0.001953515,0.0000458816,0.0008456598,0.9769397,0.00009260951,0.007218458,0.000007696201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804267,0.001696013,0.01023977,0.0001229228,0.00003398172,0.00008349563,0.001596993,0.0004113253,0.005388796],"genre_scores_gemma":[0.9652121,0.001178359,0.01528478,0.0000385407,0.00001408861,0.00008680071,0.003053735,0.0001250867,0.01500657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001882209,"threshold_uncertainty_score":0.006296575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05426104612637696,"score_gpt":0.3085947395058696,"score_spread":0.2543336933794926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}