{"id":"W1989672988","doi":"10.1006/bbrc.2001.5275","title":"Dissociation of 5′ AMP-Activated Protein Kinase Activation and Glucose Uptake Stimulation by Mitochondrial Uncoupling and Hyperosmolar Stress: Differential Sensitivities to Intracellular Ca2+ and Protein Kinase C Inhibition","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"AMPK; Glucose uptake; Glucose transporter; GLUT4; Protein kinase A; AMP-activated protein kinase; Chemistry; Intracellular; Snf3; Stimulation; Endocrinology; Internal medicine; Biochemistry; Kinase; Biology; Insulin; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004943322,0.0005031804,0.0005740479,0.0003110355,0.0003432463,0.0009317198,0.0008471597,0.0005776249,0.002305516],"category_scores_gemma":[0.0006861688,0.0005343818,0.0004869816,0.0004577329,0.0006566309,0.001004686,0.0004107592,0.001451834,0.0005904742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001170356,"about_ca_system_score_gemma":0.0007738154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002210282,"about_ca_topic_score_gemma":0.002562902,"domain_scores_codex":[0.9996557,0.00003350784,0.000030033,0.00004295829,0.00007752371,0.0001602572],"domain_scores_gemma":[0.9994484,0.0001861451,0.00007503904,0.0001151575,0.00006203489,0.0001132257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00320181,0.0001081593,0.0002180754,0.00007077178,0.00001837156,0.0001209374,0.00008895303,0.0001535293,0.991886,0.001044316,0.0001926121,0.002896462],"study_design_scores_gemma":[0.000122558,0.0001889558,0.00773389,0.000008699049,0.00001493621,0.0003044631,0.00005709246,0.001074461,0.9889656,0.000245718,0.001267796,0.00001573474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988551,0.003886161,0.002359532,0.0004363962,0.000127815,0.00004383159,0.0006958796,0.0001591251,0.003740429],"genre_scores_gemma":[0.9933344,0.001032021,0.001085664,0.0001666474,0.00003978412,0.00004660395,0.001397088,0.00005690345,0.0028408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002305516,"threshold_uncertainty_score":0.008491516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03045202771708728,"score_gpt":0.303858534897284,"score_spread":0.2734065071801968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}