{"id":"W1989704687","doi":"10.3390/molecules16010637","title":"Synthesis, Inhibitory Effects on Nitric Oxide and Structure-Activity Relationships of a Glycosphingolipid from the Marine Sponge Aplysinella rhax and Its Analogues","year":2011,"lang":"en","type":"article","venue":"Molecules","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Glycosphingolipid; Chemistry; Stereochemistry; Fucose; Glycolipid; Galactosamine; Nitric oxide; Residue (chemistry); Trisaccharide; Sponge; Ceramide; Inhibitory postsynaptic potential; Biochemistry; Glucosamine; Biology; Organic chemistry; Glycoprotein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001131316,0.0002732938,0.0001299676,0.0001240905,0.0000843111,0.0001227162,0.000133938,0.0001470863,0.0004700811],"category_scores_gemma":[0.0001601836,0.0000762266,0.0001440692,0.0001207578,0.0001225227,0.0001221104,0.00009090376,0.0002060606,0.0001099419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001439676,"about_ca_system_score_gemma":0.0001726074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005889059,"about_ca_topic_score_gemma":0.0008083269,"domain_scores_codex":[0.9999449,0.00001633312,0.000006705898,0.000009195767,0.00001037582,0.00001253778],"domain_scores_gemma":[0.9998963,0.00002437757,0.00002844083,0.000008513743,0.00001160003,0.00003074812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004045239,0.00003658994,0.0001437582,0.00005989981,0.000006156895,0.00008539206,0.00001341419,0.0002928243,0.997227,0.00004929602,0.00001599785,0.001664996],"study_design_scores_gemma":[0.00004094196,0.001245903,0.001974854,0.000008927415,0.00001813921,0.0001974116,0.00001537287,0.0002750938,0.9948257,0.00002336953,0.001368972,0.000005334251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955989,0.002687599,0.0004584797,0.00002912428,0.00001297626,0.00001642218,0.0002480086,0.000007729805,0.000940671],"genre_scores_gemma":[0.9960603,0.001392291,0.001090676,0.00002298017,0.000008187356,0.00001969292,0.0004809237,0.000004157115,0.0009207004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005889059,"threshold_uncertainty_score":0.001572549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172100922782079,"score_gpt":0.1932442682223052,"score_spread":0.1715232589944844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}