{"id":"W1989704687","doi":"10.3390/molecules16010637","title":"Synthesis, Inhibitory Effects on Nitric Oxide and Structure-Activity Relationships of a Glycosphingolipid from the Marine Sponge Aplysinella rhax and Its Analogues","year":2011,"lang":"en","type":"article","venue":"Molecules","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Glycosphingolipid; Chemistry; Stereochemistry; Fucose; Glycolipid; Galactosamine; Nitric oxide; Residue (chemistry); Trisaccharide; Sponge; Ceramide; Inhibitory postsynaptic potential; Biochemistry; Glucosamine; Biology; Organic chemistry; Glycoprotein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110296,0.0002171969,0.000271827,0.00003618328,0.0001322168,0.00002391123,0.0001383299,0.0001602015,0.0001089676],"category_scores_gemma":[0.0007195665,0.0001673682,0.00006136412,0.0001105042,0.0001046062,0.00005787736,0.0001188186,0.000261385,0.000002117608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000227901,"about_ca_system_score_gemma":0.00001610595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003477821,"about_ca_topic_score_gemma":0.00004309235,"domain_scores_codex":[0.9990981,0.00009249903,0.0001807245,0.0003167313,0.0001546007,0.0001573051],"domain_scores_gemma":[0.9980327,0.00138271,0.0001437157,0.0003301017,0.00003252992,0.00007823047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001738856,0.00004523783,0.01226906,0.0001806251,0.00009240471,0.00001903995,0.000234783,0.000001254727,0.983166,0.0000914004,0.00002594461,0.00370041],"study_design_scores_gemma":[0.0001596684,0.000007562392,0.1091762,0.0001068739,0.0001176308,0.000007190295,0.00007162715,0.0001151886,0.8893611,0.0006850786,0.00003560003,0.0001562034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961654,0.0007379082,0.000004925703,0.00004075812,0.00001663416,0.00006463812,0.0001270545,0.00003406833,0.002808603],"genre_scores_gemma":[0.9995206,0.000113992,0.0001529014,0.00002341469,0.00009096377,0.00001416743,0.00001932801,0.00002204192,0.00004261748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09690716,"threshold_uncertainty_score":0.6825076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172100922782079,"score_gpt":0.1932442682223052,"score_spread":0.1715232589944844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}