{"id":"W1989759362","doi":"10.1016/s0960-9822(00)00349-3","title":"Protein kinases: Six degrees of separation?","year":2000,"lang":"en","type":"review","venue":"Current Biology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Howard Hughes Medical Institute","keywords":"Biology; Kinase; Transcription factor; Cell biology; Protein kinase B; Gene; Protein kinase A; Signal transduction; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001724387,0.000416433,0.001005042,0.0001165223,0.00004251557,0.000008741964,0.0004712536,0.0005967509,0.0001109807],"category_scores_gemma":[0.00008539929,0.0003379819,0.0004640462,0.0001410181,0.0001969807,0.00000152387,0.0001367332,0.000234194,0.00009728885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001949872,"about_ca_system_score_gemma":0.0003823652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000879936,"about_ca_topic_score_gemma":0.00001024064,"domain_scores_codex":[0.9980195,0.0003152445,0.0006535415,0.000623813,0.00007733708,0.000310581],"domain_scores_gemma":[0.9987857,0.00002630019,0.0004303878,0.0006083521,0.00007710062,0.00007218341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000172925,0.0001351128,0.00001096454,0.003532948,0.0001597659,0.000001384406,0.000007206237,0.000003132374,0.003994445,0.0003648277,0.001591206,0.9901817],"study_design_scores_gemma":[0.0001405299,0.0003031616,7.996069e-7,0.001596107,0.0001618432,0.00001411777,0.000001146587,0.000001337084,0.00171614,0.00003263034,0.9957044,0.0003277918],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005267103,0.9972569,0.0001488362,0.000003256482,0.0004002351,0.0008141074,0.0004243716,0.0000177454,0.0004078455],"genre_scores_gemma":[0.0003613931,0.9944797,0.0001690928,0.000005607287,0.0005328151,0.0002362014,0.003915018,0.00004357641,0.0002565646],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9941132,"threshold_uncertainty_score":0.9999072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07276352497929933,"score_gpt":0.3978779540976131,"score_spread":0.3251144291183137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}