{"id":"W1989832006","doi":"10.1046/j.0022-202x.2004.22202.x","title":"CpG Oligonucleotides Elicit Antitumor Responses in a Human Melanoma NOD/SCID Xenotransplantation Model","year":2004,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Xenotransplantation; Nod; CpG site; Melanoma; Oligonucleotide; Cancer research; CRISPR; Biology; Medicine; Immunology; Transplantation; DNA; Gene; DNA methylation; Genetics; Internal medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001630214,0.0001631663,0.0002964933,0.0002296584,0.00006564974,0.00001823116,0.0002420541,0.0001461281,0.000006349127],"category_scores_gemma":[0.0001302144,0.0001480891,0.0001056131,0.0001100989,0.0002971039,0.0000250572,0.00003322436,0.0002076714,0.000007142235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003124195,"about_ca_system_score_gemma":0.0002678757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003582202,"about_ca_topic_score_gemma":0.0001491255,"domain_scores_codex":[0.9987783,0.0001374608,0.0005511027,0.0001835415,0.0001256019,0.0002239583],"domain_scores_gemma":[0.999211,0.0000201412,0.000322594,0.0001382764,0.0002074221,0.0001006154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002407765,0.00006301459,0.003750453,0.00002169936,0.00005354576,0.0002585609,0.0004816302,0.003482079,0.9901908,0.001122012,0.0003079958,0.00002744965],"study_design_scores_gemma":[0.001224231,0.0004215222,0.00882774,0.0001206269,0.00002134984,0.001232096,0.0001943238,0.0001591282,0.9798807,0.007698006,0.00006267425,0.0001576104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996044,0.0002597321,0.002308821,0.000990894,0.00005941392,0.00008019287,0.00001411117,0.000004243649,0.0002386408],"genre_scores_gemma":[0.9965215,0.000123371,0.0022568,0.0009596164,0.00006427156,0.000006109538,0.00001782155,0.00001478448,0.00003569101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01031009,"threshold_uncertainty_score":0.6038899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02323853442186113,"score_gpt":0.2819586856130134,"score_spread":0.2587201511911523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}