{"id":"W1989897941","doi":"10.1023/b:pham.0000036906.65263.da","title":"The Role of Metabolites in Bioequivalence","year":2004,"lang":"en","type":"review","venue":"Pharmaceutical Research","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"U.S. Food and Drug Administration","keywords":"Bioequivalence; Context (archaeology); Metabolite; Drug; Pharmacology; Medicine; Pharmacokinetics; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008242395,0.00140365,0.004546507,0.003874303,0.0002461612,0.002147501,0.001393573,0.002191227,0.002372825],"category_scores_gemma":[0.01787476,0.0005889463,0.001356367,0.005300258,0.002543694,0.002641085,0.0009626614,0.002943437,0.0007317652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001196141,"about_ca_system_score_gemma":0.002697989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001624658,"about_ca_topic_score_gemma":0.001825051,"domain_scores_codex":[0.9959628,0.002479301,0.0004549752,0.0002647817,0.0007857114,0.00005242071],"domain_scores_gemma":[0.972735,0.02495447,0.0009808686,0.0004229814,0.0008084102,0.00009818217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001760587,0.00006228641,0.000272215,0.03003552,0.0005491716,0.0001177908,0.00007316379,0.003974951,0.0004537397,0.03430732,0.006804913,0.9231729],"study_design_scores_gemma":[0.0003576331,0.0007376838,0.002919995,0.03008318,0.002100463,0.003435423,0.0001931922,0.007656573,0.002965667,0.2292339,0.7201204,0.0001958883],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009624751,0.9957911,0.003256156,0.0004179364,0.0001071075,0.000005247296,0.00000962471,0.000006128986,0.0003105687],"genre_scores_gemma":[0.00263199,0.9931443,0.003398184,0.0002161012,0.0004009582,0.00001983799,0.00001395711,0.000005016584,0.0001696324],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008242395,"threshold_uncertainty_score":0.04359049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9374920013793809,"score_gpt":0.7844228098714564,"score_spread":0.1530691915079245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}