{"id":"W1989991921","doi":"10.1158/1078-0432.ccr-14-2565","title":"Randomized Trial of Oral Cyclophosphamide and Veliparib in High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers, or <i>BRCA</i> -Mutant Ovarian Cancer","year":2015,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Institutes of Health","keywords":"Medicine; Cyclophosphamide; Veliparib; Ovarian cancer; Fallopian tube cancer; Fallopian tube; PARP inhibitor; Oncology; Internal medicine; Cancer; Chemotherapy; Gastroenterology; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001989877,0.001708043,0.002622218,0.0004140924,0.000503361,0.00128073,0.0009861548,0.001576512,0.007167422],"category_scores_gemma":[0.00194447,0.0008083905,0.001252835,0.0004464336,0.001471208,0.0007224883,0.0004607816,0.003445416,0.0009054784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001178187,"about_ca_system_score_gemma":0.002256195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001324324,"about_ca_topic_score_gemma":0.002429408,"domain_scores_codex":[0.9991339,0.0005169952,0.0000489927,0.0001332767,0.00005367961,0.0001131588],"domain_scores_gemma":[0.9982864,0.0004384255,0.0004088818,0.0001568423,0.00008486497,0.0006245325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.983148,0.00694225,0.0004690508,0.0002004019,0.0004117401,0.00002987078,0.00002445694,0.0002976387,0.002169654,0.00008409734,0.0004938912,0.005729026],"study_design_scores_gemma":[0.9537946,0.04453543,0.0004997373,0.00001101595,0.0001484276,0.00002161583,0.000006864942,0.0002666356,0.0003353048,0.00005678737,0.000317983,0.000005658344],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887738,0.001823372,0.0006626727,0.0007630424,0.000581374,0.00470565,0.0009735337,0.000105556,0.001611066],"genre_scores_gemma":[0.9852411,0.001269876,0.001762072,0.001315915,0.0005336216,0.00525117,0.001397148,0.00002471439,0.003204532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007167422,"threshold_uncertainty_score":0.02397746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2632031430878121,"score_gpt":0.5062227187434356,"score_spread":0.2430195756556235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}