{"id":"W1989991921","doi":"10.1158/1078-0432.ccr-14-2565","title":"Randomized Trial of Oral Cyclophosphamide and Veliparib in High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers, or <i>BRCA</i> -Mutant Ovarian Cancer","year":2015,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Institutes of Health","keywords":"Medicine; Cyclophosphamide; Veliparib; Ovarian cancer; Fallopian tube cancer; Fallopian tube; PARP inhibitor; Oncology; Internal medicine; Cancer; Chemotherapy; Gastroenterology; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.01076097,0.0004794291,0.002989412,0.0004140736,0.0001567409,0.00008252803,0.0005113417,0.0006267343,0.001091004],"category_scores_gemma":[0.003093466,0.0003384928,0.0003088347,0.001624766,0.002273105,0.0002414137,0.0003043656,0.002093257,0.00001324231],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002238479,"about_ca_system_score_gemma":0.01360859,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05455505,"about_ca_topic_score_gemma":0.01334229,"domain_scores_codex":[0.9906284,0.002315969,0.002525845,0.001240253,0.002070761,0.001218787],"domain_scores_gemma":[0.9936928,0.00278849,0.000444074,0.0009490734,0.001008826,0.001116776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9706357,0.0007920699,0.007225938,0.00035072,0.0004579676,0.0003915129,0.0006270572,0.00007613694,0.0005856124,0.0003100061,0.00806284,0.01048451],"study_design_scores_gemma":[0.9495453,0.003800244,0.005454884,0.001060684,0.0001955931,0.00004476376,0.000277008,0.0002949967,0.001283906,0.0007751046,0.03680575,0.0004617181],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9690149,0.006205068,0.00005669073,0.01439639,0.002752024,0.006009782,0.0002941113,0.00009731107,0.001173755],"genre_scores_gemma":[0.945381,0.03927544,0.001942593,0.003183923,0.002753654,0.004078708,0.00007101195,0.0001696565,0.003143956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04121276,"threshold_uncertainty_score":0.9999067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2632031430878121,"score_gpt":0.5062227187434356,"score_spread":0.2430195756556235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}