{"id":"W1989993156","doi":"10.1016/j.str.2005.08.001","title":"IRF-3 Releases Its Inhibitions","year":2005,"lang":"en","type":"letter","venue":"Structure","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Coactivator; Interferon regulatory factors; IRF1; Interferon; Cell biology; Mechanism (biology); Biology; Chemistry; Computational biology; Transcription factor; Genetics; Gene; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009758482,0.0006720453,0.0007001451,0.0002449917,0.0008082545,0.001243366,0.0007333935,0.006374579,0.004414598],"category_scores_gemma":[0.002572743,0.0002215061,0.0008428194,0.0001332929,0.001082033,0.0007453784,0.0005829408,0.01077339,0.002107519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001478914,"about_ca_system_score_gemma":0.00036937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000372163,"about_ca_topic_score_gemma":0.0004808414,"domain_scores_codex":[0.9995229,0.0001409171,0.00004061309,0.00004274863,0.0001385758,0.0001142516],"domain_scores_gemma":[0.9993348,0.0003826507,0.00004697766,0.0000982597,0.00006849442,0.00006882232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003912123,0.0004410319,0.002206064,0.0005109591,0.0002035884,0.02970266,0.0002899179,0.0007847804,0.07082303,0.0517581,0.7090381,0.1303296],"study_design_scores_gemma":[0.001561847,0.000606501,0.003261839,0.0002091108,0.000146524,0.0184396,0.0003305139,0.003329525,0.1036758,0.0375142,0.8308435,0.00008110893],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03864123,0.0232979,0.005441817,0.8318636,0.05315543,0.0001040656,0.0003203008,0.0004757745,0.04669982],"genre_scores_gemma":[0.472477,0.01265089,0.005133807,0.3871259,0.05924037,0.0002809688,0.000345108,0.000142064,0.06260372],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.006374579,"threshold_uncertainty_score":0.01476824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016570751539296,"score_gpt":0.2311284087193239,"score_spread":0.220962701203931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}