{"id":"W1989993555","doi":"10.1016/j.jconrel.2004.11.023","title":"In vitro and in vivo activities of verteporfin-loaded nanoparticles","year":2005,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"QLT (Canada)","funders":"","keywords":"Verteporfin; Nanoparticle; Phototoxicity; Chemistry; In vivo; Drug delivery; Photodynamic therapy; Nuclear chemistry; Nanotechnology; In vitro; Materials science; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006140999,0.0001044362,0.0008535954,0.0003985808,0.00001681929,0.000007287369,0.00006059088,0.00004660807,0.00004763798],"category_scores_gemma":[0.0006045792,0.00007320684,0.0001164903,0.00015055,0.0001157454,0.0001812305,0.00002068391,0.0002919385,5.196251e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001098937,"about_ca_system_score_gemma":0.0001750274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002438617,"about_ca_topic_score_gemma":0.00004009823,"domain_scores_codex":[0.9986259,0.0001192209,0.0006364665,0.00008120143,0.0003271076,0.0002101403],"domain_scores_gemma":[0.9990563,0.0003748742,0.0002692324,0.00009390766,0.00008940417,0.0001162259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03960844,0.000399797,0.0008357266,0.00003938812,0.0001571347,0.0002945445,0.0005068509,0.00003925165,0.954938,0.000009200377,0.000154278,0.003017386],"study_design_scores_gemma":[0.06492283,0.0006751477,0.007276996,0.0002930507,0.00007743536,0.0002275075,0.0007177382,0.001590213,0.9234837,0.0001613207,0.0004815568,0.000092469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920472,0.004372493,0.000003198255,0.003029811,0.0000392831,0.000288174,0.000002925161,0.000002818009,0.0002141205],"genre_scores_gemma":[0.9982121,0.001067596,0.000131551,0.0002094589,0.0000847278,0.000008198936,8.488851e-8,0.0000088887,0.0002773879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03145427,"threshold_uncertainty_score":0.2985289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00932227057738768,"score_gpt":0.2869228871636016,"score_spread":0.277600616586214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}