{"id":"W1990070722","doi":"10.1021/bi700359e","title":"Recruitment of Both Uniform and Differential Binding Energy in Enzymatic Catalysis:  Xylanases from Families 10 and 11","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Enzyme; Binding energy; Differential (mechanical device); Catalysis; Chemistry; Biochemistry; Enzyme catalysis; Biophysics; Biology; Physics; Thermodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003262995,0.0003863624,0.0003324984,0.0001109841,0.0001365402,0.0003896744,0.0003916473,0.0004418496,0.0009750652],"category_scores_gemma":[0.0003731412,0.0002788332,0.000199987,0.0001213706,0.000301522,0.0002848958,0.0004548662,0.0004768889,0.0003116998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003493435,"about_ca_system_score_gemma":0.0002193816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007433723,"about_ca_topic_score_gemma":0.0009567764,"domain_scores_codex":[0.9996729,0.00006556989,0.00001858216,0.00006070867,0.00009202655,0.00009027268],"domain_scores_gemma":[0.9998229,0.00005337429,0.00003690524,0.0000141904,0.00002385092,0.00004872468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002473366,0.00004006146,0.001366445,0.0000406814,0.00001324381,0.00009168113,0.00003077469,0.0004930368,0.9955503,0.000134892,0.00002540063,0.001966118],"study_design_scores_gemma":[0.00004090413,0.00040685,0.01585557,0.000008860383,0.00003479244,0.0006296485,0.0001043853,0.005741635,0.9757468,0.0001422841,0.001265973,0.00002232197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978276,0.0002443128,0.001459685,0.00002286071,0.000003528693,0.000004176355,0.00001749138,0.00001569296,0.0004046913],"genre_scores_gemma":[0.9982011,0.00008695145,0.001157704,0.0000211346,0.000001509151,0.00000624022,0.00006196706,0.000009267818,0.0004540207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009750652,"threshold_uncertainty_score":0.003261924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01436687381184188,"score_gpt":0.2125002158053758,"score_spread":0.1981333419935339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}