{"id":"W1990098699","doi":"10.1097/fbp.0b013e3282feb099","title":"Glycogen synthase kinase-3β heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results","year":2008,"lang":"en","type":"article","venue":"Behavioural Pharmacology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Schizophrenia (object-oriented programming); GSK-3; Heterozygote advantage; Glycogen synthase; Lithium (medication); Knockout mouse; Action (physics); Postmortem studies; Medicine; Endocrinology; Glycogen; Neuroscience; Internal medicine; Kinase; Psychology; Biology; Psychiatry; Genetics; Gene; Allele; Receptor; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001508379,0.0003517792,0.000411958,0.0002029975,0.0001166512,0.000006770334,0.0003631163,0.000295958,0.00003475617],"category_scores_gemma":[0.00007897519,0.000358395,0.0001733686,0.0002088968,0.0002880902,0.0000180333,0.0002560622,0.0002794064,0.00000554252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005202698,"about_ca_system_score_gemma":0.0004698007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000663511,"about_ca_topic_score_gemma":0.000302714,"domain_scores_codex":[0.9977977,0.0001243592,0.0007370899,0.0006488769,0.0002325769,0.0004594158],"domain_scores_gemma":[0.9991071,0.00003638228,0.0003051781,0.0002481045,0.0001444109,0.0001587751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005064955,0.0004754791,0.001408844,0.00002574133,0.00005054083,0.00006755815,0.0007293147,0.005381944,0.9857594,0.00000332324,0.0007490771,0.0002837931],"study_design_scores_gemma":[0.004812392,0.0008631361,0.00680752,0.00003274563,0.0001088752,0.0001368016,0.0002013431,0.006365403,0.9802094,0.00003584494,0.00003698096,0.0003895643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982706,0.0001014519,0.00004925354,0.0003756666,0.0001863452,0.0005629356,0.0003616666,0.00001454183,0.00007749211],"genre_scores_gemma":[0.9964617,0.0002564309,0.001623817,0.0004984432,0.00001857176,0.00005283485,0.0001621367,0.0000500621,0.0008760072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005550036,"threshold_uncertainty_score":0.9998868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05791732703105586,"score_gpt":0.3211888196326267,"score_spread":0.2632714926015709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}