{"id":"W1990123554","doi":"10.1371/journal.ppat.1002198","title":"Chlamydia trachomatis Co-opts GBF1 and CERT to Acquire Host Sphingomyelin for Distinct Roles during Intracellular Development","year":2011,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":236,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; University of California, San Francisco; Japan Society for the Promotion of Science; Canadian Institutes of Health Research; National Center for Research Resources; University of Texas Health Science Center at San Antonio; Yale University; National Institutes of Health; American Lung Association; Universiteit Utrecht; Oregon State University","keywords":"Chlamydia trachomatis; Biology; Brefeldin A; Cell biology; Chlamydiae; Vesicular transport protein; Endosome; Golgi apparatus; Ceramide; Intracellular; Vesicle; Virology; Genetics; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222738,0.0003949356,0.0002985542,0.0002520577,0.0003039211,0.0003689855,0.0003203746,0.0005127731,0.001138265],"category_scores_gemma":[0.0001590109,0.0001707013,0.0002981253,0.0002075336,0.0002774685,0.0002530907,0.0005066789,0.0006549098,0.0003707791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007655986,"about_ca_system_score_gemma":0.0005441977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00342888,"about_ca_topic_score_gemma":0.007133965,"domain_scores_codex":[0.9996892,0.00002137293,0.00002543967,0.00005652398,0.00008721206,0.0001202433],"domain_scores_gemma":[0.999886,0.00001383037,0.00003429544,0.00001855274,0.00001350644,0.00003372737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005231659,0.00001101129,0.0002287208,0.00002227275,0.000002032905,0.00004216255,0.00001129158,0.00001861679,0.9987937,0.0001105218,0.00003267856,0.0006747034],"study_design_scores_gemma":[0.000008011134,0.0001356142,0.00854762,0.000008904415,0.00001196236,0.0004480634,0.00006597014,0.0007996114,0.986333,0.00004467677,0.003586553,0.00001002147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938908,0.001342583,0.001921676,0.000232698,0.00006519125,0.00002853552,0.0008001539,0.00009384542,0.00162455],"genre_scores_gemma":[0.9934238,0.0005174506,0.002506376,0.00009891873,0.000006305687,0.0000423047,0.0006210876,0.00001814692,0.002765624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00342888,"threshold_uncertainty_score":0.006817818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02292663239536477,"score_gpt":0.2303941362877205,"score_spread":0.2074675038923557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}