{"id":"W1990171093","doi":"10.1093/molehr/gau072","title":"Single blastomere removal from murine embryos is associated with activation of matrix metalloproteinases and Janus kinase/signal transducers and activators of transcription pathways of placental inflammation","year":2014,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; U.S. Public Health Service; National Institutes of Health; Hawaii Community Foundation","keywords":"Blastomere; Biology; Andrology; Embryo; Trophoblast; Signal transduction; Cell biology; Matrix metalloproteinase; SOCS3; Placenta; Embryogenesis; Pregnancy; STAT3; Fetus; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001629148,0.0003262843,0.0002468313,0.0003014153,0.0001589354,0.0001960717,0.0001551199,0.0002958922,0.001294417],"category_scores_gemma":[0.0001609284,0.0002307977,0.000275758,0.00009118331,0.000338451,0.0001121978,0.0002028157,0.00069904,0.0001734611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001735423,"about_ca_system_score_gemma":0.0001962549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000352464,"about_ca_topic_score_gemma":0.0009743065,"domain_scores_codex":[0.9998161,0.00002541554,0.00001969203,0.00004714408,0.00005578757,0.00003588534],"domain_scores_gemma":[0.9997968,0.00003628663,0.00009575163,0.00002297504,0.000009881575,0.00003832113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001324388,0.00001703291,0.0004917282,0.00002917799,0.000004721081,0.0001133203,0.00001547576,0.00001566205,0.9985219,0.00002912778,0.00001010399,0.0006192393],"study_design_scores_gemma":[0.00002200452,0.0009994556,0.04319913,0.00001509415,0.00002743115,0.001001882,0.0000735881,0.0003250781,0.9529842,0.00006950941,0.001276744,0.000005894488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958271,0.001780631,0.001457559,0.0000649452,0.00002246067,0.00002602218,0.0001718473,0.00002628612,0.0006230709],"genre_scores_gemma":[0.9942428,0.001626586,0.001771893,0.00005423956,0.00001156968,0.0000496885,0.0003587313,0.0000104571,0.001873984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001294417,"threshold_uncertainty_score":0.004330218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01520694327095009,"score_gpt":0.2247108558065385,"score_spread":0.2095039125355884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}