{"id":"W1990171093","doi":"10.1093/molehr/gau072","title":"Single blastomere removal from murine embryos is associated with activation of matrix metalloproteinases and Janus kinase/signal transducers and activators of transcription pathways of placental inflammation","year":2014,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of General Medical Sciences; U.S. Public Health Service; National Institutes of Health; Hawaii Community Foundation","keywords":"Blastomere; Biology; Andrology; Embryo; Trophoblast; Signal transduction; Cell biology; Matrix metalloproteinase; SOCS3; Placenta; Embryogenesis; Pregnancy; STAT3; Fetus; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002395973,0.000156561,0.0003894075,0.0001441084,0.00006517075,0.000005444851,0.00002897863,0.00008993537,0.00001500877],"category_scores_gemma":[0.0001066141,0.0001439003,0.00006368406,0.0001604961,0.0001811723,0.0001474558,0.00001174946,0.0001024328,7.192129e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003719655,"about_ca_system_score_gemma":0.00002068518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001499681,"about_ca_topic_score_gemma":0.00001691813,"domain_scores_codex":[0.9987773,0.0001144909,0.0003506619,0.0003575048,0.0002984247,0.0001015971],"domain_scores_gemma":[0.9992035,0.00002648682,0.0003557838,0.0002302706,0.0001443992,0.0000395268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007518507,0.0001592521,0.001166934,0.0003088542,0.0002910914,0.000003114474,0.002016826,0.00003508041,0.9873002,0.0001224441,0.000001752458,0.007842661],"study_design_scores_gemma":[0.001877046,0.0009964991,0.03189542,0.0007376886,0.0003399161,0.00001684992,0.0003351733,0.00007412845,0.9632892,0.0003034478,0.00001983428,0.000114825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974985,0.0005149062,0.001180636,0.000126859,0.00002489009,0.0004958196,0.00001796041,0.00002714397,0.0001133451],"genre_scores_gemma":[0.9992496,0.00002700046,0.0005331811,0.000005855411,0.00003837616,0.0000122312,0.00009408309,0.00001844015,0.00002120238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03072849,"threshold_uncertainty_score":0.5868086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01520694327095009,"score_gpt":0.2247108558065385,"score_spread":0.2095039125355884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}