{"id":"W1990226405","doi":"10.1007/s11010-009-0188-0","title":"A mechanism of nucleocytoplasmic trafficking for the homeodomain protein PRH","year":2009,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"National Cancer Institute; National Institute of General Medical Sciences; U.S. Public Health Service","keywords":"Nuclear localization sequence; Nuclear transport; Importin; Cell biology; Karyopherin; Nucleoporin; Biology; Homeobox; NLS; Cytoplasm; Nuclear protein; Cell nucleus; Nuclear export signal; Transport protein; Molecular biology; Transcription factor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005855893,0.0003833214,0.0005936321,0.0003833561,0.001546419,0.001516373,0.001121194,0.001615188,0.001481842],"category_scores_gemma":[0.000531517,0.000394627,0.0005628156,0.0001927962,0.001156647,0.002560121,0.0009808078,0.001316588,0.001126005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0014805,"about_ca_system_score_gemma":0.0005779435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006096346,"about_ca_topic_score_gemma":0.0003382084,"domain_scores_codex":[0.9997538,0.00002899571,0.00001545285,0.0001010245,0.00005108132,0.00004957183],"domain_scores_gemma":[0.9998423,0.00004116651,0.00001647231,0.00005238241,0.00002270321,0.00002506164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003441964,0.0000587427,0.0005369991,0.0002284237,0.00002913596,0.00124575,0.0002463229,0.001024064,0.858817,0.1230252,0.001437634,0.01300644],"study_design_scores_gemma":[0.0001731619,0.0004812683,0.002240275,0.00003211451,0.00004130278,0.004157291,0.0002831724,0.02184751,0.9131732,0.03029078,0.02716973,0.0001101772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7688789,0.01236036,0.1835246,0.006412779,0.00139109,0.000196062,0.0003522973,0.002120139,0.02476379],"genre_scores_gemma":[0.9628336,0.002293858,0.02522768,0.0004359516,0.0001464638,0.00008736635,0.0002355587,0.00006852946,0.008671024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001615188,"threshold_uncertainty_score":0.01074189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008000885099021013,"score_gpt":0.2414242635593538,"score_spread":0.2334233784603327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}