{"id":"W1990245885","doi":"10.1021/bi9002474","title":"γ-Radiation Induced Interstrand Cross-Links in PNA:DNA Heteroduplexes","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Université de Sherbrooke","funders":"","keywords":"DNA; Oligonucleotide; Chemistry; Oligomer; Nucleotide; Base pair; Nucleic acid; Peptide nucleic acid; Nucleobase; Molecular dynamics; DNA damage; Biophysics; Biochemistry; Gene; Biology; Computational chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002119524,0.0002803211,0.0002110188,0.0001398293,0.0001352733,0.0002658713,0.0001820292,0.0003239061,0.0006202434],"category_scores_gemma":[0.0003694415,0.000216573,0.0002690727,0.0001478452,0.0002243201,0.0003051324,0.0002007872,0.0004719498,0.0001807542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000253827,"about_ca_system_score_gemma":0.0001839594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001977618,"about_ca_topic_score_gemma":0.0002229299,"domain_scores_codex":[0.9998957,0.00001832736,0.000007807133,0.00003532024,0.00002934648,0.0000135333],"domain_scores_gemma":[0.9998364,0.00006923609,0.00005810608,0.00001153128,0.00001182475,0.00001275202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007685789,0.00004290529,0.0006437304,0.0001257756,0.00004054083,0.0001918361,0.00006556654,0.01621435,0.9794304,0.000598559,0.0000402636,0.00252922],"study_design_scores_gemma":[0.00001895853,0.0002770571,0.001668698,0.00001440821,0.00002246663,0.0001580538,0.00002261204,0.02470691,0.9714173,0.0004526477,0.001226896,0.00001393033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879149,0.0008806355,0.01006563,0.00003341051,0.00002799332,0.00003902666,0.00007522485,0.00007570546,0.0008874328],"genre_scores_gemma":[0.9948947,0.0004981615,0.003900341,0.00003009593,0.000002597567,0.00003495567,0.00009248601,0.00001772001,0.0005289094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006202434,"threshold_uncertainty_score":0.002074957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007490293871389187,"score_gpt":0.2660905580544954,"score_spread":0.2586002641831062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}