{"id":"W1990308099","doi":"10.1016/j.jmb.2009.11.045","title":"Crystal Structures of an Oligopeptide-Binding Protein from the Biosynthetic Pathway of the β-Lactamase Inhibitor Clavulanic Acid","year":2009,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Biotechnology and Biological Sciences Research Council; European Synchrotron Radiation Facility; European Commission; Vetenskapsrådet; European Molecular Biology Laboratory","keywords":"Streptomyces clavuligerus; Biosynthesis; Arginine; Oligopeptide; Tripeptide; Chemistry; Biochemistry; Amino acid; Stereochemistry; Peptide; Bradykinin; Clavulanic acid; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001983205,0.0004370058,0.0005991405,0.0002238217,0.0006957067,0.0009242904,0.000856988,0.0006864729,0.001338823],"category_scores_gemma":[0.0004766881,0.0002847842,0.0002013802,0.0004385275,0.0002321255,0.0003402923,0.0002138368,0.001451066,0.0002519879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001995518,"about_ca_system_score_gemma":0.001113356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009050593,"about_ca_topic_score_gemma":0.01055474,"domain_scores_codex":[0.9998626,0.00001637258,0.000006985968,0.00002353395,0.00006137152,0.00002914234],"domain_scores_gemma":[0.999833,0.0000505783,0.00002814682,0.000005321851,0.0000353968,0.00004761298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004337253,0.001581515,0.01131861,0.001563658,0.0004372625,0.006208164,0.00122917,0.02424163,0.8859244,0.0147211,0.02159484,0.02684256],"study_design_scores_gemma":[0.00272795,0.001345562,0.07448992,0.0002965057,0.0006190864,0.006552537,0.00238306,0.2514442,0.5653453,0.005274567,0.08922217,0.0002991346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859729,0.004126089,0.00183826,0.001018537,0.0001470766,0.00003803374,0.001495647,0.0001492657,0.005214174],"genre_scores_gemma":[0.9790481,0.003854551,0.004840491,0.0002569416,0.00003685357,0.00005034288,0.007198505,0.00005137499,0.004662699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009050593,"threshold_uncertainty_score":0.01799583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008301475597758822,"score_gpt":0.2452834446895925,"score_spread":0.2369819690918337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}