{"id":"W1990366850","doi":"10.1074/jbc.m313164200","title":"A Study of the Protection of Plasmin from Antiplasmin Inhibition within an Intact Fibrin Clot during the Course of Clot Lysis","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; U.S. Public Health Service; Heart and Stroke Foundation of Canada","keywords":"Fibrin; Plasmin; Fibrinolysis; Chemistry; Lysis; Biophysics; Antifibrinolytic; Biochemistry; Immunology; Enzyme; Internal medicine; Biology; Tranexamic acid; Medicine; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004849482,0.0003446437,0.0005082447,0.0003228333,0.0001708034,0.0005107453,0.0003422409,0.0005141679,0.0008161445],"category_scores_gemma":[0.0008532412,0.0002202356,0.0003242902,0.0003861085,0.0002546391,0.0005121664,0.0001469034,0.000963316,0.000407458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003080299,"about_ca_system_score_gemma":0.0002738976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007694605,"about_ca_topic_score_gemma":0.0004445795,"domain_scores_codex":[0.9996461,0.00005212612,0.00002028411,0.00009025529,0.0001007992,0.00009045925],"domain_scores_gemma":[0.999247,0.0002626736,0.0002144632,0.0000881126,0.00009872614,0.0000891356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002310811,0.00003704879,0.0003813308,0.00004422373,0.00001305349,0.00005673449,0.00005977032,0.00007674185,0.9973077,0.00006001209,0.00002617405,0.001706121],"study_design_scores_gemma":[0.00002663903,0.001237871,0.02090806,0.00001025873,0.00003563191,0.0003637593,0.00004312806,0.002852346,0.9727517,0.00009413918,0.00165602,0.00002040871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863755,0.00367041,0.008599057,0.00004472436,0.00002865002,0.00004839828,0.0003162288,0.00004893247,0.0008679883],"genre_scores_gemma":[0.9922064,0.001350665,0.004091692,0.0000488884,0.00002026514,0.00005195396,0.000620588,0.0000187416,0.001590851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008161445,"threshold_uncertainty_score":0.00273025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0186294072922211,"score_gpt":0.2411180519689214,"score_spread":0.2224886446767003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}