{"id":"W1990385569","doi":"10.3390/genes6020216","title":"Genetic Mosaics and the Germ Line Lineage","year":2015,"lang":"en","type":"review","venue":"Genes","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Biology; Genetics; Somatic cell; Germline; Lineage (genetic); Mutation; Point mutation; Germline mutation; Exome; Genome; Germ cell; Germline mosaicism; Zebrafish; Soma; Exome sequencing; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003822376,0.0005319891,0.0007856008,0.002589075,0.0002763792,0.0009987435,0.0005770634,0.001061092,0.002748886],"category_scores_gemma":[0.0007470292,0.0002172656,0.000287918,0.001473695,0.0009085646,0.001229468,0.0006770377,0.001238612,0.001116013],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00058438,"about_ca_system_score_gemma":0.0009527594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001121252,"about_ca_topic_score_gemma":0.001320373,"domain_scores_codex":[0.9998118,0.00003613502,0.00002816083,0.00003626638,0.00006980815,0.00001787488],"domain_scores_gemma":[0.9997063,0.0001728969,0.00003941143,0.000009015022,0.00004982879,0.00002249106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004778389,0.00003140092,0.0006487917,0.01063078,0.00005386087,0.001319829,0.0002518648,0.000331791,0.002601861,0.01633116,0.02364765,0.9441032],"study_design_scores_gemma":[0.00000520914,0.0000225771,0.001185342,0.002597398,0.00003809641,0.008201282,0.00009644124,0.0000414901,0.0004456677,0.004228558,0.9831263,0.00001161508],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000224184,0.9973575,0.0001474226,0.0002719584,0.0001026739,0.000002608912,0.00001032741,0.000007066831,0.001876167],"genre_scores_gemma":[0.001616573,0.9971617,0.0001592633,0.0002035024,0.0001252257,0.00000400144,0.00002375302,0.00000200858,0.0007038623],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002748886,"threshold_uncertainty_score":0.009195924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0767470230026217,"score_gpt":0.3535391799838338,"score_spread":0.2767921569812121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}