{"id":"W1990422646","doi":"10.1002/prp2.76","title":"Analysis of FK506, timcodar (VX‐853) and FKBP51 and FKBP52 chaperones in control of glucocorticoid receptor activity and phosphorylation","year":2014,"lang":"en","type":"article","venue":"Pharmacology Research & Perspectives","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; College of Graduate Studies, University of Toledo; National Institutes of Health; School of Medicine, New York University; York University; Stranahan Foundation; National Institute on Minority Health and Health Disparities; University of Toledo Foundation","keywords":"FKBP; Phosphorylation; Glucocorticoid receptor; Receptor; Endocrinology; Internal medicine; Glucocorticoid; Chemistry; Molecular biology; Biology; Cell biology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007277816,0.0002415391,0.0002005375,0.0001171328,0.0001139253,0.0002083748,0.0001787324,0.0001944071,0.0007819016],"category_scores_gemma":[0.00005059167,0.00009323462,0.0002563352,0.000113361,0.0001480055,0.0001394789,0.00009520978,0.0002446285,0.0001934259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002324582,"about_ca_system_score_gemma":0.000100515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004964856,"about_ca_topic_score_gemma":0.0006544068,"domain_scores_codex":[0.9999257,0.00001056967,0.000009388088,0.00001703395,0.00001366449,0.00002348104],"domain_scores_gemma":[0.9999398,0.00000728034,0.00002199198,0.000006548361,0.000004421531,0.00002002872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001253953,0.000006721242,0.0001432872,0.00001090596,0.000002593858,0.0000206792,0.000003311675,0.00001854167,0.999383,0.00003213554,0.000005624045,0.0002476902],"study_design_scores_gemma":[0.00002419073,0.0002670698,0.0183781,0.000004259944,0.00002967872,0.000305783,0.00003052074,0.0007704601,0.9788682,0.00003022702,0.001286748,0.000004893033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974916,0.001154043,0.0006564548,0.0000468381,0.00001187776,0.00000760336,0.0001921657,0.00001449715,0.0004248279],"genre_scores_gemma":[0.9972806,0.0006183713,0.0006049498,0.00002732006,0.000005653309,0.00001534374,0.0004005399,0.000006187187,0.001040991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007819016,"threshold_uncertainty_score":0.00261569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02004510093708877,"score_gpt":0.3588516178492234,"score_spread":0.3388065169121346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}