{"id":"W1990425673","doi":"10.1002/jgm.1501","title":"Development of an inflammation‐inducible gene expression system using helper‐dependent adenoviral vectors","year":2010,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness; Cystic Fibrosis Foundation","keywords":"Genetic enhancement; Transgene; Gene; Gene expression; Inflammation; Reporter gene; Biology; Gene delivery; Vectors in gene therapy; Viral vector; In vivo; Vector (molecular biology); Cancer research; Immunology; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007800813,0.0007014524,0.0003669553,0.0004919549,0.00021606,0.0004954824,0.0006967753,0.0005627555,0.001543006],"category_scores_gemma":[0.0003341155,0.0003724812,0.0004373476,0.0002248698,0.0004445893,0.0004623752,0.0003881545,0.001538187,0.0009254501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003881005,"about_ca_system_score_gemma":0.0005564388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002894339,"about_ca_topic_score_gemma":0.0002557461,"domain_scores_codex":[0.9996374,0.00005107039,0.00005252728,0.00008034678,0.0001242105,0.0000544985],"domain_scores_gemma":[0.9997119,0.0000791169,0.00007062782,0.00003791721,0.00004161481,0.00005880075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008132888,0.0000605309,0.0001274588,0.0001103499,0.00000742215,0.00006375747,0.00002920216,0.0001664012,0.9948578,0.0005795592,0.0001082808,0.003807859],"study_design_scores_gemma":[0.00005761623,0.0003555829,0.0003508404,0.00001685194,0.00003143811,0.0002725275,0.00001075123,0.001297591,0.9888383,0.0001037771,0.008653765,0.0000109252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.549816,0.004257141,0.4336026,0.0006233178,0.0007610116,0.001894005,0.001608734,0.00202425,0.005412995],"genre_scores_gemma":[0.6920444,0.004292092,0.2882555,0.0001729381,0.0001285672,0.0009603636,0.004659547,0.0002567231,0.009229854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001543006,"threshold_uncertainty_score":0.005161881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02983781322076525,"score_gpt":0.3151011286353779,"score_spread":0.2852633154146126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}