{"id":"W1990433002","doi":"10.1016/j.vaccine.2012.09.036","title":"A simple approach for enhanced immune response using engineered dendritic cell targeted nanoparticles","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Biotinylation; Ovalbumin; Antigen; Streptavidin; Dendritic cell; Immune system; Chemistry; Fusion protein; Immunogenicity; Splenocyte; Biotin; Biology; Recombinant DNA; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001713118,0.0004585124,0.0003139135,0.0001920194,0.0001997497,0.0003677978,0.0003365536,0.0006908677,0.0007350357],"category_scores_gemma":[0.0001387755,0.0001893789,0.0003455249,0.000103259,0.0002152694,0.0003800164,0.0003741771,0.0009317731,0.0004563075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002491292,"about_ca_system_score_gemma":0.0002800497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000177083,"about_ca_topic_score_gemma":0.0002951054,"domain_scores_codex":[0.9998449,0.00001886944,0.00001214007,0.00003871463,0.00006371615,0.0000215283],"domain_scores_gemma":[0.9999419,0.00001021973,0.00001207295,0.00001273637,0.00001240071,0.00001068885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003457886,0.00005032976,0.00003768457,0.00005525218,0.00000747973,0.00005844905,0.000009683637,0.00009983147,0.9934919,0.000844278,0.0002574075,0.005053118],"study_design_scores_gemma":[0.00001933177,0.0001310537,0.0001155834,0.000003508731,0.00001268938,0.0002338311,0.000004718556,0.000752706,0.9916003,0.000254464,0.00686475,0.000007062623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6054022,0.008003278,0.3648829,0.002522587,0.00189662,0.000737076,0.0005852866,0.001274058,0.01469602],"genre_scores_gemma":[0.8228291,0.002769957,0.1573627,0.0009338731,0.0001022555,0.0003376882,0.0003993335,0.0001116858,0.01515348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007350357,"threshold_uncertainty_score":0.00245899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01567519031162078,"score_gpt":0.2481320075475287,"score_spread":0.2324568172359079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}