{"id":"W1990433002","doi":"10.1016/j.vaccine.2012.09.036","title":"A simple approach for enhanced immune response using engineered dendritic cell targeted nanoparticles","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Biotinylation; Ovalbumin; Antigen; Streptavidin; Dendritic cell; Immune system; Chemistry; Fusion protein; Immunogenicity; Splenocyte; Biotin; Biology; Recombinant DNA; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007461642,0.0002711766,0.0004109388,0.0001689728,0.000299876,0.00001789644,0.000225158,0.0002275821,0.0004895844],"category_scores_gemma":[0.0002408334,0.0002444574,0.0001744041,0.00023759,0.00002665741,0.0002174227,0.00005605452,0.0001809134,0.0001138033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006097011,"about_ca_system_score_gemma":0.00006041833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002737823,"about_ca_topic_score_gemma":3.179842e-7,"domain_scores_codex":[0.9980333,0.0004057741,0.0004438254,0.0002431612,0.00003369713,0.0008402769],"domain_scores_gemma":[0.9988995,0.0004377752,0.0001229661,0.000422238,0.00008156629,0.0000360116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008294436,0.0003991317,0.0001216662,0.00003808552,0.0001419035,5.000218e-7,0.0005803308,0.00006614594,0.9894688,0.00003995793,0.0004413727,0.0004076403],"study_design_scores_gemma":[0.004342286,0.0003091233,0.006394281,0.00001153544,0.00007520047,0.00003841333,0.0003969315,0.0001185618,0.9739195,0.00001160105,0.01407539,0.0003071439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9521397,0.03518504,0.01145419,0.0000314841,0.0004291161,0.0005587983,0.00003780577,0.0001249072,0.00003890471],"genre_scores_gemma":[0.9953901,0.00005530308,0.002190862,0.00008742508,0.00005888319,0.0001041384,0.0001770793,0.000057222,0.001878985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04325035,"threshold_uncertainty_score":0.9968686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01567519031162078,"score_gpt":0.2481320075475287,"score_spread":0.2324568172359079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}