{"id":"W1990473825","doi":"10.1126/science.1222195","title":"Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota","year":2012,"lang":"en","type":"article","venue":"Science","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":679,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Crohn's and Colitis Foundation","keywords":"Virulence; Pathogen; Microbiology; Biology; Citrobacter rodentium; Commensalism; Colonization; Human pathogen; Aeromonas veronii; Specific-pathogen-free; Bacteria; Gene; Virology; Genetics; Aeromonas","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002065079,0.000589533,0.0002717797,0.0002805098,0.0001436919,0.0006158483,0.0002631342,0.0004455354,0.0007574319],"category_scores_gemma":[0.0002446334,0.0001672451,0.0002008375,0.0001030513,0.0006329384,0.0004248686,0.0003801854,0.0006601895,0.0003425553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000333876,"about_ca_system_score_gemma":0.0002394078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002582343,"about_ca_topic_score_gemma":0.0003302525,"domain_scores_codex":[0.9996786,0.00006474766,0.00001826658,0.00006243723,0.00008050633,0.00009540444],"domain_scores_gemma":[0.9994156,0.0001090966,0.00022004,0.00007527626,0.00006008465,0.0001198747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002619324,0.00001088036,0.0002743394,0.000007516321,6.973555e-7,0.00002983683,0.000006093686,0.00001581661,0.9992198,0.00008254359,0.000007321704,0.0003188665],"study_design_scores_gemma":[0.00001147893,0.0003995099,0.02350676,0.00000803567,0.00001105215,0.0006943859,0.00008747666,0.001606736,0.9724263,0.0003277691,0.0009073924,0.00001316638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938958,0.001359625,0.003291785,0.0001941636,0.00002037412,0.00001044014,0.00007311424,0.00008426078,0.001070481],"genre_scores_gemma":[0.9969473,0.0004368264,0.001694324,0.0000402598,0.000009103778,0.00000863658,0.00009507087,0.00001442349,0.0007541226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007574319,"threshold_uncertainty_score":0.002533853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006813794999366652,"score_gpt":0.2508705853805157,"score_spread":0.244056790381149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}