{"id":"W1990479271","doi":"10.4161/cc.9.19.13463","title":"The CINSARC signature: Prognostic and predictive of response to chemotherapy?","year":2010,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Institute of Cancer Research; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale","keywords":"Biology; Chemotherapy; Signature (topology); Cancer research; Oncology; Computational biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001303296,0.0004583758,0.001881132,0.0004900084,0.0009385434,0.001765499,0.0007532781,0.009423119,0.007359034],"category_scores_gemma":[0.006847736,0.0002804317,0.0005637336,0.0006780664,0.0009389928,0.001571022,0.0004239581,0.00914863,0.002603345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00179423,"about_ca_system_score_gemma":0.001356245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001753532,"about_ca_topic_score_gemma":0.004283343,"domain_scores_codex":[0.9993039,0.0002431542,0.00008307003,0.0001046157,0.0001156786,0.0001495875],"domain_scores_gemma":[0.9979776,0.001127419,0.0001841103,0.00007028227,0.0002993823,0.0003412632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002039195,0.0003199519,0.122282,0.0003924264,0.0001757803,0.01505808,0.0003824481,0.001088156,0.004754547,0.006954312,0.6441264,0.2024268],"study_design_scores_gemma":[0.001452293,0.001341319,0.1462467,0.001246643,0.0005986116,0.04391194,0.002389038,0.008767488,0.003000472,0.0437042,0.7470899,0.0002514037],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01954924,0.008017904,0.0002582746,0.9525917,0.005568873,0.00003430163,0.0003684553,0.00003052882,0.01358079],"genre_scores_gemma":[0.2871603,0.02255342,0.001331053,0.5259404,0.1340625,0.0002367653,0.000589389,0.00006580313,0.02806039],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.009423119,"threshold_uncertainty_score":0.02461839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004754859271061607,"score_gpt":0.2633352078185665,"score_spread":0.2585803485475049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}