{"id":"W1990479271","doi":"10.4161/cc.9.19.13463","title":"The CINSARC signature: Prognostic and predictive of response to chemotherapy?","year":2010,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut National Du Cancer; Institute of Cancer Research; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale","keywords":"Biology; Chemotherapy; Signature (topology); Cancer research; Oncology; Computational biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001000465,0.0001431768,0.0002005217,0.0000559018,0.00008343319,0.0000157419,0.0000771401,0.000394858,0.00004074184],"category_scores_gemma":[0.00007968335,0.00008763948,0.00005491911,0.00008579085,0.00009729996,0.00001493074,0.00002280189,0.0008766284,0.000009950168],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004432639,"about_ca_system_score_gemma":0.0001496213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001454552,"about_ca_topic_score_gemma":0.000002894374,"domain_scores_codex":[0.999254,0.00004186076,0.0001350861,0.0002141241,0.0001859212,0.0001690357],"domain_scores_gemma":[0.9990652,0.0003875292,0.00007800849,0.0003128133,0.00009355216,0.0000629221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001051217,0.00008237538,0.0005500847,0.0001566174,0.0002145534,0.00008820049,0.00136217,0.000001756376,0.008515729,0.000001457963,0.9846891,0.003286746],"study_design_scores_gemma":[0.001313048,0.0007473396,0.01397064,0.0001266507,0.0004319572,0.00001476266,0.0000598952,0.00001766719,0.005293543,0.0001137723,0.9777966,0.0001140844],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1518414,0.002320817,0.00006207766,0.8377088,0.00048424,0.00234586,0.0002439724,0.00004539885,0.00494745],"genre_scores_gemma":[0.5763616,0.0002321687,0.0007730483,0.3874195,0.00166717,0.0003218977,0.0002496297,0.0001240239,0.03285101],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4502893,"threshold_uncertainty_score":0.3808563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004754859271061607,"score_gpt":0.2633352078185665,"score_spread":0.2585803485475049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}