{"id":"W1990507217","doi":"10.1038/nrc1631","title":"Antisense therapy for cancer","year":2005,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":399,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"","keywords":"Cancer; Nuclease; Antisense therapy; Oligonucleotide; Cancer research; Biology; Gene; Genetic enhancement; Cancer cell; Computational biology; Bioinformatics; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005269792,0.001168769,0.001232535,0.001463856,0.0003186493,0.0006834323,0.0009247806,0.001390542,0.00544464],"category_scores_gemma":[0.0003718088,0.0003664464,0.0004820412,0.001127485,0.0006910132,0.0007765023,0.0007634738,0.00296869,0.004171207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006102331,"about_ca_system_score_gemma":0.0004332875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006754572,"about_ca_topic_score_gemma":0.002326871,"domain_scores_codex":[0.999842,0.00002483582,0.00001178721,0.00002865584,0.0000710763,0.0000216219],"domain_scores_gemma":[0.9998786,0.00004884171,0.0000186499,0.000006481261,0.00002919151,0.0000182012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001185206,0.0001089671,0.0001228362,0.003345886,0.00006312606,0.0003194812,0.00004906745,0.0004311679,0.01416664,0.009071651,0.08836749,0.8838352],"study_design_scores_gemma":[0.00003772589,0.00006953997,0.0003050744,0.0005464377,0.00003748221,0.001152897,0.00001316403,0.0001203396,0.001674953,0.002607315,0.993422,0.00001309402],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002871147,0.989819,0.001537397,0.0009185798,0.001498459,0.00001936516,0.00004292143,0.00004656332,0.005830643],"genre_scores_gemma":[0.003161493,0.9814897,0.00132032,0.001558017,0.0006975075,0.00004758219,0.0001286437,0.00001111329,0.01158564],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00544464,"threshold_uncertainty_score":0.01821417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0441429174720454,"score_gpt":0.416710876922098,"score_spread":0.3725679594500526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}