{"id":"W1990519747","doi":"10.1091/mbc.e09-05-0420","title":"Dissection of Combinatorial Control by the Met4 Transcriptional Complex","year":2009,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Regulon; Promoter; Biology; Transcription factor; Cofactor; DNA-binding protein; Gene; DNA; Saccharomyces cerevisiae; Genetics; Activator (genetics); Transcriptional regulation; Cell biology; Biochemistry; Enzyme; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001909493,0.0004215024,0.0002575974,0.0002997006,0.0002367521,0.0006261423,0.0004670586,0.0001899082,0.0008458658],"category_scores_gemma":[0.0002968229,0.0003438999,0.0002363834,0.0001947881,0.0004006349,0.000256611,0.0007702443,0.000592263,0.0004529152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009112274,"about_ca_system_score_gemma":0.0003286175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008694365,"about_ca_topic_score_gemma":0.002262701,"domain_scores_codex":[0.9997223,0.00003846744,0.00002270274,0.00007692098,0.000093079,0.00004651978],"domain_scores_gemma":[0.9997562,0.00004896163,0.0000659563,0.0000457352,0.0000292556,0.00005405879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009178861,0.000008419594,0.0004032949,0.00001331583,0.000003517483,0.00002304604,0.000007412247,0.0002139023,0.9978576,0.0002733033,0.00001387815,0.001090372],"study_design_scores_gemma":[0.00001292259,0.00004127694,0.002263882,0.000004068569,0.00001214588,0.0001378501,0.00002339791,0.004480121,0.991184,0.0001833783,0.001650187,0.00000679623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897194,0.0004647432,0.008495595,0.00005370623,0.000009866408,0.00001424744,0.0002179361,0.00008301882,0.0009413542],"genre_scores_gemma":[0.9920939,0.000187557,0.005488929,0.00002429297,0.000005180185,0.00002212073,0.0006005717,0.00005362295,0.001523737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009112274,"threshold_uncertainty_score":0.006611407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00751684974161384,"score_gpt":0.2555938491747655,"score_spread":0.2480769994331517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}